CYCLIC CHANGES IN UTERUS AND OVARIES. 13 



medium-sized good follicles, a number of follicles in a medium 

 stage of connective tissue atresia, and there are a large number 

 of follicles in the last stage of connective tissue atresia. The 

 surface and glandular epithelium is cylindrical, of medium height 

 and is almost without mitoses; a few isolated mitoses may be 

 found in the gland fundi. The cell layer of the connective tissue 

 contains many mitoses; there are some small mononuclear, and 

 a few polynuclear leucocytes in the mucosa. 



Six days after heat, the corpora lutea of the former period are 

 quite vacuolar and in process of degeneration. There are good 

 new corpora lutea and many good small, medium-sized and large 

 follicles, and many follicles in the last stages of connective tissue 

 atresia. The surface epithelium of the uterus is cylindrical and 

 of medium height; the epithelium of the gland ducts and gland 

 fundi is cuboidal-cylindrical. There are nowhere mitoses present 

 in the epithelium. There are mitoses present in the connective 

 tissue cell layer of the mucosa, but the mitoses are here probably 

 not as frequent as at five days after the previous period of heat. 

 There are many small mononuclear cells in the connective tissue. 



Seven days after heat, we find good corpora lutea, many good 

 small medium-sized and large follicles, no follicles with granu- 

 losa degeneration and many follicles in the last stage of con- 

 nective tissue atresia. The epithelium of the surface and glands 

 of the uterine mucosa is cuboidal or cylindrical of medium height. 

 No mitoses are present in the epithelium; some mononuclears 

 can be found in the surface epithelium. In the connective tissue 

 cell layer there are a number of mitoses, but not as many as five 

 days after heat. Some polynuclear leucocytes and small mono- 

 nuclear cells are in the mucosa and some nuclei disintegrate in 

 the upper layer of the connective tissue. 



Eight days after heat, the condition of the ovaries is the same 

 as seven days after the period of heat, but degeneration of the 

 granulosa has now set in in some of the larger follicles. The 

 corpora lutea of the former period are quite vacuolar and are in 

 full process of retrogression. The epithelium of surface and 

 glands of the uterus is cuboidal or cylindrical of medium height, 

 without mitoses. In the connective tissue of the mucosa we 

 still see blood vessels running towards the surface and at right 



