CYCLIC CHANGES IX UTERUS AND OVARIES. 15 



Twelve days after heat. There are many good small, medium- 

 sized and large follicles; some large follicles show granulosa 

 degeneration. A number of follicles show early and medium 

 and some advanced connective tissue atresia. The follicles 

 which had arrived about six to seven days after copulation at 

 the last stage of connective tissue atresia are disappearing more 

 and more. Some mature follicles may be present. 



The surface and glandular epithelium of the uterus is cuboidal- 

 cylindrical; some small mononuclear cells migrate through the 

 surface epithelium. No definite mitoses can be seen in the 

 surface epithelium. A few isolated gland ducts and the ad- 

 joining surface epithelium have high cylindrical epithelium. 

 The mucosa is narrow and the nuclei of the connective tissue 

 are small. 



Fourteen days after heat. In the corpora lutea some vacuoliza- 

 tion begins in the periphery. There are good, small medium- 

 sized and large good follicles, some large follicles show granulosa 

 dgeneration; other follicles are in the early or medium or a later 

 stage of connective tissue atresia. These follicles which are now 

 constantly degenerating all contribute to the follicles in the late 

 stages of connective tissue atresia which we find at the time of 

 heat. 



The surface and gland duct epithelium of the uterus is cuboidal 

 or cylindrical of medium height. The gland fundi are smaller. 

 There are some mitoses present in the surface and gland duct 

 epithelium. The mucosa is low, the connective tissue nuclei 

 are small. There is some edema present in the connective tissue 

 which may even raise up the surface epithelium. There may be 

 some dilated glands with polynuclear leucocytes and some 

 mononuclears in the mucosa. 



Fifteen days after heat. At this time the ovaries are about the 

 same as fourteen days after heat. There are good small, medium- 

 sized and large follicles; a number of large follicles show granulosa 

 degeneration. A certain number of follicles are in the medium- 

 or medium-late stages of connective tissue atresia. There are 

 not many follicles in the last stage of connective tissue atresia. 

 The follicles which degenerated at the period of the last heat 

 have almost disappeared and the other degenerating follicles 



