20 LEO LOEB. 



burnt three days, twenty hours after copulation; twenty and one 

 half hours later incisions were made into the uterus and fourteen 

 days, seventeen hours after copulation, ovaries and uterus were 

 examined. There were mature follicles present in the otherwise 

 typical ovaries. The uterus was similar as in No. 270. The 

 uterus was also similar in No. 391, where two days, seven hours 

 after ovulation, the right ovary had been excised and one corpus 

 luteum of the left ovary. Five days later the uterus had been 

 incised and seventeen days after the last copulation ovaries and 

 uterus were examined. No mature follicles were found in the 

 ovaries. 



In one case (No. 687) the corpora lutea had been extirpated 

 seven days, seven hours after copulation and ten days later the 

 uterus and ovaries were examined. In the uterus two preg- 

 nancies were found ; the mucosa of the uterus above and below 

 the decidua was poor in nuclei and fibrillar. In the ovaries there 

 were mature follicles, but no new ovulation had as yet taken place. 



We may conclude that in cases in which after an early extir- 

 pation of the corpora lutea no new ovulation takes place, the 

 condition of the uterus does not undergo any marked changes. 



As we stated previously in the majority of cases in which within 

 the first week after ovulation the corpora lutea had been cut 

 out with scissors a new ovulation takes place between the eleventh 

 and sixteenth day after ovulation. If we examine the uterus in 

 these animals we find the typical structure which we might expect 

 in accordance with the time since the last ovulation. 



(1) No. 669. Forty-nine hours after last copulation, extirpa- 

 tion of the corpora lutea. Examination of the ovaries and 

 uterus twenty days after the last copulation. Examination of 

 the ovaries revealed that an ovulation had taken place about 

 seven to eight days previously; correspondingly we find in the 

 uterus the typical condition: rather low cylindrical surface 

 epithelium, small glands with the same epithelium, in the con- 

 nective tissue of the mucosa small vesicular nuclei, pressed 

 together; mitoses are lacking in epithelial as well as connective 

 tissue cells. 



(2) No. 772. Two days, seventeen hours after last copulation 

 extirpate corpora lutea; examine uterus and ovaries not quite 



