28 LEO LOEB. 



corpora lutea was partly filled by connective tissue. In the 

 uterine niucosa processes of regeneration took place after abor- 

 tion, polynuclear leucocytes migrated through the mucosa. 



(14) No. 673. Four days, two and a half hours after copula- 

 tion, one corpus luteurn was excised in each ovary. At the 

 examination fourteen days later one pregnancy was found in 

 the right horn; in the left horn there was a dilated part. In 

 the left ovary about three to four days previously two follicles 

 had ruptured (fourteen to fifteen days after the previous copu- 

 lation; new corpora lutea had formed). In the left uterus we 

 found cuboidal to cylindrical epithelium of the surface without 

 mitoses; some epithelium was raised by edematous fluid; the 

 gland ducts were drawn out; the connective tissue cells in the 

 mucosa showed many mitoses. It is possible that an abortion 

 had taken place in the left horn of the uterus and that this 

 complication may explain the cell proliferation in the connective 

 tissue. 



(15) No. 1219. Three days, nineteen hours after copulation, 

 one corpus luteum was excised in each ovary. Examination 

 ten days later showed two pregnancies in left, one in right horn 

 of the uterus. In the ovaries we found good follicles of small to 

 medium size, many follicles are in a condition of early or medium 

 connective tissue atresia. In one ovary there is a young corpus 

 luteum with a central cavity; some blood vessels begin to grow 

 into the corpus luteum. Ovulation had taken place about one to 

 two days previously (about twelve to thirteen days after copula- 

 tion). In the uterus we find cuboidal or cuboidal-cylindrical 

 surface epithelium in which there are vacuoles caused by im- 

 migrated cells. There are some rare mitoses in the surface 

 epithelium. The epithelium of the glands is low cuboidal or 

 cuboidal to cylindrical and is without mitoses. The connective 

 tissue is fibrillar and contains small nuclei ; no mitoses are present. 

 The early pregnancy prevents the cyclic changes in the uterus. 



We see, therefore, that during pregnancy the typical cyclic 

 changes as we described them above do not take place. Instead 

 we find on the whole the characteristic structure of the pregnant 

 uterus. There are two or three specimens in which some doubt 

 about the interpretation of the structural condition of the uterus 



