IJ2 PREPARATION OF THE SUBSTRATES 



originating from a morbus Basedowi would be subject 

 to decomposition. Just as every case examined has to 

 be thoroughly tested by clinical means, and its further 

 course closely followed up, so also must the substrate 

 to be employed be characterized exactly. A bare 

 statistical compilation of cases, with percentage 

 accounts of faulty diagnoses is unworthy of scientific 

 publication. Each separate case must be clinically 

 investigated. This is the reason why the fruits of 

 these researches are bound to fall into the hands of 

 clinical observers. The physiologist can only note 

 one case after another without being able to charac- 

 terize them individually, or even to observe them 

 continuously, and, in consequence, we can expect 

 little help from his side. 



A very important question is whether, instead of 

 human organs, the corresponding organs of animals 

 may be used in experiments with human serum. 15 It 

 would naturally be a great advantage in all these 

 researches if this were the case. Our earliest re- 

 searches enabled us to state the fact that human 

 placenta can be replaced by that of animals, and vice 

 versa. 16 We have made further experiments with the 

 brain and other organs, and have obtained good 

 results. It seems that organs which have the same 



15 Compare here also p. 27. 



16 Compare also the works of Schlimpert and Issel (Lit. 

 74), of v. Hippel (Lit. IIQ), Fuchs (Lit. in). 



