226 



HISTOLOGY. 



individuals. Pathologically the vacuoles may be large and have a wider 

 distribution. Glycogen (page 51) occurs in granules and larger masses, 

 especially after abundant meals. In the fasting condition the cells are 

 relatively small, dark, and obscurely outlined, but during digestion they 



become larger, with a clear central part 

 and dark periphery (Fig. 255). In man 

 both conditions may be found in one liver. 

 The bile, secreted by the hepatic cells, 

 frequently contains drops of fat and pig- 

 ment granules such as occur within the 

 cells. It is eliminated through the bile 

 capillaries. 



Bile capillaries. The hepatic trabec- 

 ulae, as they proliferate from the diver- 

 ticulum, form a network of solid cords. 

 Within the cords a slender lumen de- 

 velops later, apparently beginning at the periphery of the lobule 

 and extending toward the center. It causes such cords as consist of only 

 two rows of cells to resemble the tubules of other glands, as shown in the 

 diagram Fig. 256. In uninjected sections the lumen, if cut across, appears 

 as a minute circle midway along the line of contact between two hepatic 



, Gland 

 lumen (bile 

 capillary). 



FIG. 255. LIVER CELLS OF MAN. X 560. 



A, Isolated liver cells containing smaller 

 and larger fat drops, f. ; b., imprint 

 from contact with a blood vessel. B, 

 From a section; i, empty cells; 2, cells 

 filled with secretion. 



Blood vessels. 



FIG. 256. DIAGRAM OP A TUBULE OP 

 THE LIVER (DISREGARDING THE 

 ANASTOMOSES WITH ADJOINING 

 TUBULES). 



Sinusoids. 



Fio. 257. SECTION OP THE LIVER OP A RABBIT WITH THE 



BILE CAPILLARIES INJECTED. X 560. (Not a Diagram.) 



Two of the cells are each in contact with four sinusoids 



(i, 2, 3, 4) and four bile capillaries, x, a bile capillary 



where three cells meet. 



cells. Its sharp contour is aspribed to a cuticular formation belonging to 

 the cells which bound it. In longitudinal view it appears as a dark inter- 

 cellular line suggesting a cell wall. Both views are shown in the injected 

 specimen Fig. 257, where, however, those seen longitudinally seem to dis- 



