CHANGES IN THE OVARY 



119 



changes which chiefly concern the chromatin of the nucleus 

 may be summarised as follows : 



I. Early changes : (a) Protobroque cells, Variety a. The 



FIG. 23. Various stages in the development of the Graafian follicle of the 



rabbit. (From Schafer.) 



A, from young rabbit showing Pfliiger's egg-tubes ; B, C, D, E, successive 



later stages. 



nuclei are granular in appearance, the chromatin is arranged 

 irregularly, and there is no reticulum. These are the original 



