288 



HISTOLOGY 



The interlobular ducts are lined with simple columnar or cuboidal 

 epithelium. They anastomose with one another, and have'blind pockets; 

 in the larger ducts, there are branched mucous glands. The connection 

 between the ducts and the hepatic trabeculae is difficult to observe, and it 

 was once thought that the ducts with their ramifications produced the bile, 

 leaving the parenchyma for the function of internal secretion. Through 

 injections, however, or by using the Golgi method, the connections between 

 the bile capillaries and the bile ducts can be readily demonstrated (Fig. 

 283). They are found at the periphery of the portal canals, and were 



-vjr 



Branch of portal 

 vein. 



Small interlobu- 

 lar bile-duct, 

 continuing in 

 bile capillaries. 



Large interlobu- 

 lar bile-duct. 



Branch of hepat- 

 ic artery. 



Bile capillaries. ' 



Tf.' 



Wall of the central vein. 

 FIG. 283. GOLGI PREPARATION OF THE LIVER OF A DOG. X24O. 



described histologically by Hering (Strieker's Handbuch, Leipzig, 1871). 

 On the side toward the connective tissue these "canals of Hering," or 

 periportal ducts, exhibit a flat or cuboidal epithelium, like that of ordinary 

 ducts; but toward the lobule they are bounded by hepatic cells, or by flat 

 cells interrupted by hepatic cells (Fig. 284). Thus the hepatic trabeculae 

 are directly inserted into the walls of the ducts, and the bile capillaries con- 

 nect with the lumen. 



The hepatic, cystic and common bile ducts all have a simple columnar 

 epithelium, with occasional goblet cells and branching mucous glands. 

 Around the hepatic duct there is a wide zone formed by the ramifying 

 ducts of these mucous glands, as they extend into the surrounding con- 

 nective tissue. The connective tissue layer is said to contain many elastic 



