ANESTHESIA 



189 



The experiments with alcohol lead to somewhat differ- 

 ent results. In the first place, alcohol is not so toxic as 

 ether, chloroform, or chloral hydrate, and higher 

 concentrations must be used to produce the same effects 

 on permeability. In sea water containing alcohol 0.051 M, 

 or 2.955% by volume, (the solution being renewed every 



x Chlopq/brm 0.05 % 

 * O.T % 







11CH 

 % 



100- 



90- 



80 



TIX-K 



-o. 



O 



100 



200 



300 



MINUTES 



Fio. 82. Curve B shows the net electrical resistance of Laminaria agardhii in sea water; 



Curve A in sea water containing 0.05% chloroform, Curve C placed for 80 minutes 



in sea water containing 0.1% of chloroform and then put back into sea water. 



15 minutes) the results were much the same as in 0.099 M 

 ether (the solution being renewed every 5 minutes), 

 except that the rise in resistance took place more slowly, 

 sometimes occupying 30 minutes or more. It was found 

 that 0.2385 M, or 13.8757o by volume, is decidedly toxic. 

 An interesting feature of the results with alcohol is 

 that the increase of permeability is reversible. If the 

 increase be carried too far it is not reversible (or at 



