CONNECTIVE TISSUE CARTILAGE BONE 



r 



L_ . 



FlG. GO. PlGMENTED CELLS FROM THE 



CHOROID COAT OF THE Ox's EYE. 



Unstained; hence, only the pigment 

 granules appear in the figure. 1, gran- 

 ules contained within the cytoplasm; 2, 

 free granules which have escaped from 

 cells injured during the process of teas- 

 ing; 3, the non-pigmented nuclei. 



less flattened and are often closely applied to, or even wrapped around. 



the fiber bundles. These lamellar cells have a small nucleus, a consider- 

 able rim of cytoplasm, which fre- 

 quently has a shrunken appearance, 

 and sometimes a few short cytoplas- 

 mic processes. The branching stel- 

 late forms, however, are characteris- 

 tic of the younger connective tissues. 

 In certain locations a deposit of 

 pigment granules occurs within the 

 connective tissue cells. Such pig- 

 ment cells are usually found where 

 protection against light seems desir- 

 able, and are most abundant in the 

 choroid coat and iris of the eye. 

 The pigment granules are entirely 

 confined to the cytoplasm of the 

 cell ; the nucleus is never invaded by 

 the deposit. These granules belong 

 to the melanin series of pigments. 

 The cytoplasm of certain cells found in connective tissue contains 



coarse basophil granules, which stain with dahlia and similar basic 



dyes. This type is known as lasopliil granule cells, 



or mast cells (Mastzellen of the German authors). 



The granules of other granulocytes are readily stained 



with acid dyes, such as eosin (eosinopliil, acidopliil 



or o.i'i/jiliil granulocytes). According to the observa- 

 tions of II. B. Shaw (Jour. Anat. and Physiol., 



1901), certain of the granule cells abound in those 



locations where fat is deposited, and have a special 



relation to the development of the fat cells of adipose 



tissue. These granulocytes of fibro-elastic connective 



tissue are apparently identical with those of the blood. 



Lymphocytes and phagocytic leukocytes are also pres- 

 ent in connective tissue. 



It is a disputed point whether the granulocytes of 



connective tissue different-late from fibroblasts or 



from lymphocytes; the weight of evidence seems to incline to the latter 



position. Plasma cells seem more probably altered fibroblasts but have 



also been regarded by some as lymphocyte derivatives. The so-called 



i 



FIG. 61. GRANTLE 

 CELLS FROM THE 

 FIBROUS CON- 

 NECTIVE TISSUE 

 OF THE HUMAN 

 MAMMARY GLAND. 



A, a basophile 

 cell; B, an eosino- 

 phile cell. Henia- 

 tein and eosin. X 

 750. 



