590 



INTERNAL SECRETION 



Athyrosis, operative, changes follow- 



ing* ?i , 72 



Asthenia in Addison's disease, 164 

 following suprarenal suppression 



156 



Asthma thymicum, 122 

 Atropine, paralysis of vagal nerve 



endings by, 200 

 and pilocarpine, action compared, 



Auto-intoxication in pancreatic dia- 



betes, theory of, 423 

 Auto-nephrotoxins, formation of, 443 



BARIUM chloride, action of, altered by 



increase in doses of ergot, 231 

 Basophile cells, 308 

 Batrachians, suprarenal capsules in, 



299 



Benzoic acid, affinity for glycocoll, 9 

 Bile, secretion, increased by adrena- 

 lin, 212 



Biology, problems of, solved by 

 doctrine of internal secretions, 23 

 Birds, acute tetany in, 41, 42 

 , castration in, results of, 378 

 , heart of, action of adrenalin on, 



202 

 , perversion of sex characteristics 



in, 365, 366 



, portal system of suprarenals pre- 

 sent in, 300 

 , suprarenal capsules in, 128, 130, 



133, 299., 300 



, thyroid apparatus in, 36 

 Bladder, urinary effect of pituitary 

 extract on, 326 



action of adrenalin on, 205 

 , experiments to determine, 205 

 , innervation of, differences in mam- 

 mals, 205, 206 



, experiments to deter- 

 mine, 205 

 Blood, action of thymus extract on, 



121 



--, adrenalin in, 250, 251 

 --, disappearance, 256-258 

 , remaining after cessation of 



specific action, 258 

 , ultimate fate of, 255 

 , see also Adrcnalscniia 

 , alkalinity of, disappearance of 



adrenalin under, 256 

 , changes in, following extirpation 



of suprarenals, 157, 158 

 , following thyroidectomy, 66 

 , cholesterinester in, source of, 292 

 , circulation of, and humoral path- 

 ology, 2 



in suprarenals of mammals, 

 300, 301 

 , pulmonary, effects of adrenalin 



on, 185 

 , composition of, action of adrenalin 



on, 214 

 j effect of castration on, 388 



Blood formation, influence of thyroid 

 gland on, 37 



, sugar-contents of, on what de- 

 pendent, 428 



--, toxicitv after extirpation of supra- 

 renals, 156 



Blood-letting in tetany, 56 



Blood-pressure, action of adrenalin 

 on, 213 



, altered by previous adminis- 

 tration of ergot, 231, 232 

 of methylaminoketone on, 213 



, condition of, after extirpation of 

 suprarenal capsules, 147, 148 



, effect of intravenous injection of 

 organic extracts on, 21, 22 



of pituitary extract on, 323 

 - of renal extract on, 442, 443 



, fall of, induced by cholin, 276, 277 



, increase induced by suprarenal 

 extract, how abolished, 157 



, intracranial conditions governing, 



329 



, permanent increase following con- 

 tinuous transfusion of adrenalin, 

 259 



, rise in, due to adrenalin, 183, 184 



Blood-serum, mydriatic, 262 



Blood-supply to kidney, action of 

 adrenalin on, 212 



Blood-vessels, contraction, drugs in- 

 ducing, 200 



, contraction following injection of 

 adrenalin, 196 



, dilatation, drugs inducing, 200 



, effect of pituitary extract on, 326 



, portion of, acted on by adrenalin, 

 187 



, pulmonary, effect of adrenalin on, 

 negative, 197 



, toxic action of adrenalin on, 240 



Boiling, activity of thymus extract 

 not affected by, 121 



Bones, changes in, in acromegaly, 333 



, growth of, effect of pituitary ex- 

 tract on, 328 



, influence of generative glands 

 on, 382 



Brain, blood-vessels of, dilated by 

 adrenalin, 185 



, fourth ventricle, puncture of, and 

 experimental adrenalin-glycos- 

 uria, 219 



of pigs, lipoid substances in, 

 290, 291 



, relationship of tetany to, 60, 61 

 -, weight of, in gigantism, 342 



Bronchi, muscles of, action of adrena- 

 lin on, 208 



CACHEXIA, chronic, following thyroid- 

 ectomy, 63 



, following total thyroidectomv, 71, 

 72, 73 



, strumipriva and Graves's disease, 

 symptoms common to, Q9 



