5 88 



INTERNAL SECRETION 



.Adrenalin action, experiments to de- 

 termine nature, 202 



- neutralized by apocodein, 203 



- on heart of cold and warm 

 blooded animals compared, 202 



- on lachrymal glands, 212 



- on lymphatics of peritoneum, 



213 



- on metabolism, 214, 215 



- on muscles, 228, 229 



- on organs innervated by sym- 

 pathetic system, 189 



- on pancreas, 212 



- on pigment cells and granules 

 of frog, 214 



- on pregnant uterus, altered by 

 ergot, 232 



- on pupil, 230 



- on respiration, 235 



- on salivary glands, 211 



- on submaxillary glands, 211 



- on sweat-glands, 214 



- on sympathetic and autonomous 

 nervous system compared, 230, 



231 



- contrasted, 231 



- on urinary bladder, 205 



- on uterus, 200, 207 



- as quantitative test, 207 

 , therapeutic, 207 



, amount in suprarenal capsules, 



182, 248, 249 



, modification by path- 

 ological conditions, 249 

 , antagonism of cholin to, 276, 278 

 , by-effects of, 234-236 

 causing abortion, 207 



mydriasis in Graves's disease, 



21 I 



, cells producing, 253 

 , chemical tests for, in liquids and 

 secretions, 180, 181 



- , colorimetric methods, 

 181, 182 



- contents in cats and rabbits 

 compared, 251 



- of dog, 254 



- of suprarenals in Addison's 

 disease, 250 



, conversion of tyrosin into, 180 



, destruction of, factors in, 256, 257 



, diabetes, 220 



--, disassimilatory hormone, 206 

 -, disassociation of auricular and 



ventricular beats under, 203 

 , drugs antagonistic to, in action, 



200 

 , effects after thyroidectomy and 



thyroparathyroidectomy, 54, 55 

 , modified by previous adminis- 

 tration of curarin, 196, 197 



- determined by Meyer's method, 

 1 99 



- on arteries, 198 



- on coronary vessels of heart, 

 186 



Adrenalin, effects on heart, how and 

 when determined, 200 



- on nerve-endings, 197, 198 



- on pigment in Addison's disease,. 

 165 



- on pulmonary circulation, 185 



- vessels negative, 197 



- on thyroid gland, 28 

 , excretion of, 256 



- of lymph from thoracic duct 

 promoted by, 213 



, formation of, relation to chemical 



processes of muscles, 296 

 , function of, 266 



, connected with sympathetic 



system^ 266, 267 

 Adrenalin-glycosuria, 215, 259, 429 



- accompanied by hyperglycsemia,. 

 216 



, effect of subcutaneous injection 



of chyle on, 431 

 , experimental, and puncture of 



fourth ventricle, 219 

 , inhibition of, 220, 221 



, by fever, 221 (footnote) 

 , by hirudin, 221 

 , by lymphagoga, 221 

 , by pancreatic extract, 429 

 , by pilocarpin, 226 

 , mechanism of, 217, 218 

 Adrenalin in blood, 250, 251 

 , disappearance, 256-258 

 , persisting after cessation of. 



specific action, 258 

 , ultimate fate of, 255 

 , see also Adrenalaemia 

 in collapse, 188, 189 

 in heart failure, iS'S, 189 



- following diphtheria, 189 

 , increases secretion of bile, 212 



, inhibitory influence on activity of 



pancreas, 221, 226 



, injection of, contraction of blood- 

 vessels following, 196 



followed by glycosuria after 

 parathvroidectomy, 68 

 , not followed by glycosuria in 



thyroidectomized animals, 68 

 , intravenous injection, antidote to 

 poisoning by chloral, 201 



- causing dilatation of cerebral 

 vessels, 185 



- in urine, method of testing for, 182 

 , isolation methods, 177, 178 

 , matrix of, 180 



mydriasis, inhibition of, 220 

 , neutralization of strychnine by,. 



295 



, organic composition, 179, 180 

 , physiological activity, 183 



effects on sympathetic system, 

 196 

 poisoning, symptoms of various 



animals dying from, 238 

 , portion of blood-vessels acted on 



by, 187 

 , precursors of, 296, 297 



