592 



INTERNAL SECRETION 



Conarium, see Pineal body 



Corpus luteum, function of, 400, 402, 



407 

 - , hypothesis, 404 



, menstruation originating in, 



406 



verum, cells of, similarity of 

 cells of suprarenal cortex to, 269 

 Crabs, parasites causing neuter charac- 

 teristics in, 367 

 Cretinism, endemic, 79 

 , and athyrosis, So 

 , clinical signs, 79 

 , deaf-mutism in, 79 

 , geographical distribution, 79 



, same as that of endemic 

 goitre, 8 1 

 , in animals, 83 

 , metabolism in, 89 

 , treatment by thyroid extract, 



8 7 . 



Cryptorchidism, suppression of sper- 



matogenesis, 393 



, unilateral, 393-394 



Curarin, effects of adrenalin, modified 

 by previous administration of, 

 196, 197 



Cyanophile cells, 308 



Cytotoxins, specific, attempted de- 

 struction of suprarenal capsules 

 by, 144 



DEAF-MUTISM in endemic cretinism, 79 

 Decomposition, products of, effects of 



over-irritation by, 15 

 , formation in intestinal canal, 7 

 Dercum's disease, sec Adi-posis dolorosa 

 Diabetes, changes in pancreas in, 432 

 , clinical, and experimental pan- 

 creatic, analogy between, 431, 432 

 , duodenal, 422 

 , pancreatic, 220 



and auto-intoxication, 423 

 , experimental in animals of 

 different species, 414 



-, in dog, 414 

 , failure of organo-therapy in, 



423, 424 



, glycosuria in, factors in- 

 fluencing, 416, 417 

 , metabolism in, 415 

 , mydriasis characteristic of, 



production, 431 



, nervous origin, theorv of, 422 

 , permanent factors originating, 



432 



, theories respecting, 420-432 

 , see also Adrenalin-diabetes 

 Diet, effect on glycosuria in pan- 

 creatic diabetes, 416 

 Digestive tract, action of adrenalin 



on, 203, 204 



Dimorphism, sexual, 361 

 Diphtheria, heart failure following 

 adrenalin administration in, 189 

 Diseases, reflex manifestation of, 2 

 Diuresis due to pituitary extract, 327 



Diuretic action of thyroid extract, 91 



, adrenalin as, 212 



Dog, acute tetany in, 39, 40 



, adrenalin contents of, 254 



, effects of large doses of adrenalin 

 and extract of chromamne bodies 

 on, 236 



, effects of ligature of excretory 

 ducts of pancreas on, 430 



j effect of thyroidin on, 92 



, emaciation in, following extirpa- 

 tion of pancreas, 420 



, extirpation of hypophysis in, 319, 

 320 



, parathyroid glands in, 35 

 , supernumerary, 35 



, production of pancreatic diabetes 

 in, 414 



, suprarenal capsules in, experi- 

 mental removal, 141 



, thymus gland in, 113 



- , extirpation, results, 114, 117 



- implantation into, 119, 120 

 , thyroidectomized, changes in, 65 



, staggering gait of, 61 

 , toxic action of adrenalin on, 240 

 Ductless glands, functions of, early 

 discoveries, 3 



, importance of, 17 

 Duodenum, see Diabetes, duodenal 

 Dwarfism, 78 



, athyrosis and, So 



Dystrophia adiposogcnitalis, 17, 345 



ECK's fistula, formation of, leading to 



ammonia poisoning, 10 

 Eels surviving removal of suprarenal 



capsules, 153 

 Eggs, fertilization of, 356 

 Electric current, thymus gland and 



reaction of motor apparatus to, 



1 20 



Emaciation in Addison's disease, 164 

 following extirpation of pancreas, 



420 

 - following extirpation of supra- 



renals, 154 



, following thyroidectomy, 66 

 Embryo, development of hypophysis 



in, 313 



Enzymes, organic substances formed 

 by, in process of decomposition 

 of sugar, 426 



P^osinophile cells of hypophysis, 308 



Epilepsy, colloid in hypophysis, as 

 cause of, 305 



Epinephrectomy, sec Suprarenal cap- 

 sides extirpation 



Epinephrin, 178 

 -, toxic dose, 236 



Epiphysis, see Pineal body 



Epoophoron, 410 



Ergot, administration of, increase in, 

 alters action of adrenalin, 231 



, alters action of adrenalin on preg- 

 nant uterus, 232 



