INDEX 



599 



New-born infants, pineal gland in, 



, Sexually differentiated tissues 

 in, 361 



Nicotine, action of, altered by increase 

 in doses of ergot, 231 



_ effects confined to vegetative ner- 

 vous system, IQ5 



_, particular ganglion cells affected 



by, 1 94 , 



Nitrogen, excretion after reduction ot 



renal parenchyma, 445 

 ? metabolism of, in Graves s disease, 



99 



Nutrient secretions and hormones, dis- 

 tinction between, 13 



OBESITY associated with hypophysal 

 changes, 345 



, origin of types ot, 3^5 



3 reduction by thyroid extracts, 91 



Organic extracts, intravenous injec- 

 tion, effect on blood-pressure, 



21, 22 



3 physiological action, 21, 22 



. , toxic action, 21 

 Organotherapy, 20 



after experimental extirpation ot 



suprarenal capsules, 165-168 



t failure in pancreatic diabetes, 423, 



424 

 , forerunners ot, 2 



in Graves's disease, 100 

 , uses of, ii 



Organs of body, chemical correlation, 



j experimental extirpation, ad- 

 vantages, 18 

 , by-effects, 19 



} internal secretory, 6 



} partial destruction, 19 



, potential energy, 10 

 Ossification, effect of extirpation of 



thymus on, 117, n8 

 ? influence of generative glands in, 



382 

 , retardation of, following thyroid- 



ectomy, 63 

 Osteomalacia, relationship to genital 



glands, 387 



Ovarian extract, effects of, 380 

 Ovaries, relationship of, to chlorosis, 



388 



, transplantation of, 380 

 Ovary, influence of X-rays on, 403 

 , internal secretion of, 398-406 

 , interstitial tissue of, 399, 42 

 , relationship to menstruation, 381 

 Ovotestis, 363 

 Ovulation, connection of menstruation 



with, 403, 406 

 Ovum, nidation of, 408 

 Oxidation, increased, following extir- 

 pation of pancreas, 420 

 Oxybutyric acid, 419, 420 



PANCREAS, action of adrenalin on, 212 



Pancreas, agency in influence of thy- 

 roid apparatus on carbohydrate 

 metabolism, 4.1 

 , changes in, in diabetes, 432 



effects on metabolism, 70 

 , excretory ducts, experimental liga- 

 ture, results, 436 



, absorption of fat after, 



, external secretion, mechanism ot, 



extirpation, deposition of glycogen 



in liver after, how effected, 430 

 __ __ 5 experimental, change in meta- 

 bolism following, 420 

 . ? increased oxidation follow- 

 ing, 420 



. , emaciation following, 420 



_ , partial, not followed by gly- 



cosuria, 4^5 



of large portions followed by 



slight glycosuria, 416 

 , total, followed by cessation of 

 fat absorption, 437 



. } followed by glycosuria, 413 ; 



see also Diabetes (pancreatic) 



. _ 3 reduction of glycogen in 



liver under, 4 l & 

 -, function of, inhibitory, 2 1 1 



? in relation to decomposition ot 



sugar, 426 

 -, internal secretion of, 412 



, inhibition followed by gly- 

 cosuria, 428 



- of formation of sugar 



in liver by, 430 



- secretory activity of, action ot 

 adrenalin and, 220 



, inhibited by adrenalin, 



221, 226 



, limiting action of adrena- 

 lin, 226 



. , elements of, 432-438 



, function, 18, 421, 423 



_ , acini and islands of 



Langerhans concerned in, 43^, 



437 



, transplantation experimental, 422 

 and metabolism of sugar, 424, 425 

 and thyroid gland, relationship 



between, 60,, 70 

 , see also Hormones, pancreatic ; 



Langerhans^ islands of 

 Pancreatic extract, inhibition of 



adrenalin glycosuria by, 429 

 Paralysis agitans, cause of, 46 

 Parathyroid extract, 49 



, physiological activity, 49, 5p 

 - , treatment by, of post-operative 



tetany, 49 



glands, accessory, 31 

 , anatomy, 31 



, colloid in, 33 



. . , comparative anatomy, 34 



, development, 34 

 -, effect on metabolism, 70 



