410 ELIZABETH KINNEY. 



the conclusions of Meves (Marshall and Vorhies, '06; Yorhies, 

 '08; Maziarski, 'n; Nakahara, '17). 



(b) Observations. Within the nuclear membrane, which can 

 usually be distinguished with little difficulty in the spinning- 

 gland cells of //. cunea, bodies of two sizes are always present 

 (except in the anterior conducting region) and with great regu- 

 larity and frequency a larger, third body is also found (Fig. 5). 

 The smallest bodies are by far the most abundant and tend to 

 nil the entire nucleus. With certain fixatives, Bouin, Zenker, a 

 reticulum can be distinguished, upon which are arranged these 

 smallest bodies. This is not the case, however, after fixation in 

 Regaud, Champy, Benda, or Gatenby, for in the middle and 

 posterior regions of the gland the bodies always appear to be 

 free in the nucleus, forming a compact mass of small granules, 

 and take a basic stain. (See chart.) These bodies have been 

 considered as chromatin. In the anterior region of the gland, 

 these bodies are consistently present although considerably more 

 scattered. 



The second group of bodies present in the nucleus exhibits 

 considerable variability both of size and distribution. These are 

 the macrosomes or nucleoli of previous workers, but in this 

 paper, they will be referred to as "nuclear bodies." It is only 

 rarely that these nuclear bodies are found in the nuclei of the 

 conducting cells, and when they chance to be present, are 

 considerably smaller than similar bodies in the posterior or 

 middle regions. No general rule can be given for the shape or 

 dimensions of these nuclear bodies as they tend to vary greatly. 

 Their usual shape is spherical or ellipsoid, and this is typical 

 of their form in the middle region, but toward the posterior end 

 of the gland where there are evidences of active secretion indi- 

 cated by droplets in the lumen and on the edge of the lumen, 

 these bodies are often elongated and irregular in shape. In size, 

 there is variation in length between 0.5 micron and 2 micra and 

 occasionally a few are larger. Even within the same nucleus, 

 such variation in si/e is present. The bodies have no special 

 arrangement in the nucleus but tend to be dispersed throughout 

 ilx- area, very often approaching the nuclear membrane. They 

 have even been seen penetrating the nuclear wall into the cyto- 



