Il6 CARL R. MOORE. 



spermatozoa. The testicular blood supply must of course 

 remain undisturbed. 



From three to five months after replacing the degenerate 

 abdominal testis in the scrotum, the animals were killed and the 

 testes so preserved and sectioned in paraffine as to make available 

 entire cross sections of the organ from different regions. In 

 some cases tests for motile sperm in the epididymis were made 

 immediately after death. In every case autopsy revealed the 

 replaced testis in a somewhat unfavorable condition for normal 

 activity in as much as adhesions with the tunica vaginalis had 

 formed; many times the testis with its fat body was firmly 

 attached by adhesions to the bottom of the scrotum. Under 

 such conditions the growth of the fat body undoubtedly brings 

 excess pressure to bear upon the organ and in many cases the 

 entire replaced testis was practically surrounded by fat. All 

 such abnormal conditions minimize the chance of the testis 

 being able to acquire its complete gametogenetic function. In 

 a few cases adhesions were so formed that the position of the 

 replaced testis was the equivalent of an inguinal canal retention 

 or even lower abdominal retention ; under all conditions, however, 

 a portion of the testis came within the upper limits of the scrotum 

 and was subjected to some extent to its influences. 



OBSERVATIONS. 



The observations here reported are based upon the most 

 recent series of operations, involving a group of ten guinea pigs, 

 in each of which one testis was removed from the scrotum to the 

 abdomen at intervals from the ijth to the 42d day after birth 

 involving no interference with the opposite testis (see Table I.). 

 In nine animals the unilateral cryptorchid testis was replaced 

 in the scrotum four or five months later; the tenth unilateral 

 testis was removed at 4^ months abdominal retention (animal 

 No. 5) and prepared for histological study to serve as a control 

 for the type of testis replaced in the scrotum of the other nine 

 animals. In seven animals the opposite normal test is was 

 removed during the operation for replacement of the cryptorchid 

 testis and in the other two (Nos. 3 and 7) the normal testis 

 remained intact throughout the experiment. The animals were 



