124 



CARL R. MOORE. 



upper portion of the scrotum; in reality it was more nearly- 

 abdominal than scrotal. On recovery, however, the testis was 

 very evidently much larger than at the time of the replacement 





 



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FIG. 5. Seminiferous tubules from guinea pig testis (144-208) elevated to 

 abdomen thirty days after birth, remaining in abdomen four months, replaced in 

 scrotum for three months (no recovery of function). //, interstitial tissue; st, 

 degenerate tubules. 



operation. Histological sections show that the majority of the 

 seminiferous tubules were in active spermatogenesis, but very 

 few of the tubules had developed to the stage of spermatozoon 

 formation. Many of the tubules, though possessed of an active 

 germinal epithelium, contained degenerating cells, multinuclear 

 protoplasmic masses, and many vacuoles in the central portion 

 of the epithelium. In other words, the testis was quite similar 

 to testis grafts, heat applied testes, and subcutaneous testes in 

 which spermatogenesis has continued but was usually never 

 complete; the testis is not in an optimum environment for 

 normal tubular activity. The few spermatozoon bearing tubules, 

 however, show that the testis was in a position just on the 

 effective borderline with a few tubules capable of completing 

 spermatozoon formation. 



