94 BENSLEY. [VOL. II. 



distal limb, the latter curving cephalad above the ventral pos- 

 terior margin of the liver, before passing into the midgut. 



Four regions may now be distinguished ; a very short ante- 

 rior region without glands, provided with a ciliated epithelium, 

 a region with flask-shaped glands and ciliated epithelium, 

 a third region with tubular or saccular glands and a mucige- 

 nous epithelium, and finally, at the posterior end, a region in 

 which no glands at all are to be discerned. The second and 

 third regions gradually merge into one another, but the pos- 

 terior non-glandular portion is sharply marked off and forms, 

 in part at least, the future pyloric gland region. 



At this stage the two pulmonary diverticula open into a 

 capacious pouch lying below the foregut, into the floor of which 

 it opens. In longitudinal sections the first gland appears 

 immediately behind this sac. Farther back more glands make 

 their appearance, and at the point where the foregut begins to 

 enlarge into the stomach, it is completely encircled by six or 

 eight of these large flask-shaped glands. Farther back again 

 the glands become less and less flask-shaped and take on a 

 tubular or saccular character. 



One of these anterior glands is represented in Fig. 4 as 

 seen after staining in haemalum, followed by neutral gentian. 



The shape of the cells in the body of 

 the gland varies with the degree of dis- 

 tention. There seems to be in these 

 glands an accumulation of the secretion 

 in the lumen distending it, for it is only 

 by the application of a distending force 

 from within that the extreme stretching 

 of the cells, which may be commonly 

 observed, could be produced. In many 

 glands where this distention is great 



FIG. -c-Ambiystoma larva , 4 the cells are quite flattened and spread 



mm . in length ; oesophageal 



gland. Apoch. 2 mm., comp. out over a great surface, reminding one 



strongly of the appearance in the mam- 



malian blastodermic vesicle at the time of its rapid expansion. 

 The explanation there of the flattening of the cells is clearly 

 the stretching caused by the rapid transudation of fluid into 



