ISO J. DUESBERG. 



will appear to be split at one end. The resemblance of these 

 bodies to the crystalloids of Reinke is accentuated by the fact 

 that, in rare cases, they are found surrounded by a clear space, 

 located in a sort of vacuole. 



The second type is not quite so frequently noted as that just 

 described. It is represented by what appear to be thin rods, 

 pointed at both extremities, which vary considerably in length 

 in the different cells. The shorter ones are usually straight, the 

 larger ones curved. In most of the cells they are multiple (Fig. 

 5). These, too, are seen most clearly after fixation with Benda's 

 fluid, but are preserved in other fixatives also. In Regaud's 

 preparations, however, I was never able to find them. Similar 

 bodies exist in the cells of Sertoli. If I were to venture a com- 

 parison it would be to liken them to the bodies described by 

 Lubarsch in the human testicle under the name of Charcot- 

 Bottchers crystals. The so-called Lubarsch crystals are, as 

 Lenhossek has pointed out, located in the spermatogonia, but 

 there is in the seminal epithelium another form of crystalloids, 

 also described by Lubarsch (the Charcot-Bottcher crystals), 

 which are larger and are located in the cells of Sertoli. According 

 to Montgomery (1911) and to Winiwarter (1912, 2), the two 

 forms are in genetic relation. Montgomery, who unfortunately 

 failed to compare his observations with those of previous authors, 

 described them in the "antepenultimate spermatogonia" of man 

 as "rods," and came to the interesting conclusion, corroborated 

 by Winiwarter (1912, 2), that "the presence of the rod determines 

 the line of the Sertoli cell" (p. 368). Crystalloids have also been 

 found in the Sertoli cells of the pig by Bouin and Ancel (1903, 

 Fig. n) and possibly in the cat by Hague (1914). I did not 

 see anything resembling the numerous small crystalloids de- 

 scribed by Lenhossek (p. 68, Figs. 2, 3 and 4), which correspond, 

 in my opinion, to Winiwarter's (1912, i) "grains riziformes." 



The chondriosomes of the interstitial cells in mammals have 

 been seen by Jordan (1911), Winiwarter (1912, i), and Ras- 

 mussen (1917). As stated above, Jordan merely mentions their 

 presence in the opossum. Winiwarter gives a longer account 

 of these bodies in man, where he finds both granules and rods. 

 Rasmussen describes in the woodchuck small granules, "the only 



