CONTENTS 



CHAPTER I 



PAOE 



INTERNAL PROTECTIVE SECRETIONS ..... 1 



1. Theory of glandular organs and secretory processes. Historical 

 development (Malpighi, Ruysch, Haller, J. Miiller). 2. Glands with 

 no excretory ducts ; their importance as organs of internal secretion. 



3. Structure and mode of secretion of thyroid and parathyroid glands. 



4. Cachcxia thyreopriva after total thyroidectomy in man : analogy with 

 spontaneous myxoedema and cretinism. 5. " Tetania thyreopriva" 

 in man. 6. Varying effects of thyroidectomy in various animals. 

 7. Criticism of hypotheses put forward to explain effects of thyroid- 

 ectomy. 8. Experimental basis for theory of auto-intoxication resulting 

 from functional deficiency of thyroids. 9. Thyroid grafts : injection of 

 thyroid juice and thyroid feeding in therapeutic treatment of cachexia 

 thyreopriva. 10. Theory of specific functional independence of thyroid 

 and parathyroids. 11. Specific protective function of pituitary gland 

 (glandular portion of hypophysis). 12. Structure of suprarenal bodies 

 (adrenals) and paraganglia. 13. Clinical observations and physio- 

 logical experiments on protective function of the suprarenal bodies. 

 14. Double function of medullary (or paragangliar) and cortical part 

 of suprareuals. 15. Experimental injection of suprarenal extract. 

 16. Active principles of suprarenal and paragangliar system (adrenaline, 

 paragangline). Physiological action. Bibliography. 



CHAPTER II 



EXTERNAL DIGESTIVE SECRETIONS ... .67 



1. Structure of salivary glands : cranial and sympathetic inner- 

 vation. 2. Nervous mechanism of secretion in salivary glands. 

 3. Cytological changes in secretory epithelium during rest and secre- 

 tion. 4. Selective activity of salivary glands. 5. Chemical analysis of 

 salivary glands and the various kinds of saliva. 6. Structure of 

 pancreas. 7. Innervation and mechanism of its secretion. ' 8. Pan- 

 creatic juice. 9. Internal function of the pancreas. 10. Factors 

 concerned in internal pancreatic secretion. 11. Structure of gastric 

 mucosa and glands. 12. Innervation. 13. Gastric juice and the cells 

 which secrete it. 14. Zymogens which give rise to the gastric enzymes. 



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