OF ALBUMINURIA. 19 



disease in which the latter is present, as after 

 long continued suppurative or other albuminous 

 discharges. 



From reflecting on the great obstruction to the 

 circulation through the minute vessels of an inflamed 

 part, I was led to imagine, that by preventing the 

 return of blood from the kidney in one of the lower 

 animals, and taking care not to injure the artery in 

 the experiment, a condition of the organ, similar to 

 that present in acute nephritis, would be produced, 

 which might throw some light on those points in 

 which the latter disease differed from the acute stage 



O 



of granular kidney. Accordingly I cut down to and 

 exposed one kidney in a rabbit and tied the renal 

 vein, returning the organ immediately into its natural 

 position with the artery uninjured. The animal died 

 about fifteen hours afterwards, and on examination 

 the kidney in question was the only organ found 

 affected ; it was intensely congested and very much 

 enlarged, being nearly twice the bulk and weight of 

 the healthy organ ; of a dark red or blackish colour, 

 in some places soft and easily torn, and the granular 

 appearance on its surface more distinct than natural, 

 as if from enlargement of the granules. On making 

 a section it was throughout intensely gorged with 

 blood, which seemed infiltrated into the cellular 

 tissue of the organ : there tvas a little bloody urine in 

 the bladder which contained two or three minute 

 coagula, and became nearly a solid mass on applying 

 heat. This experiment was repeated with precisely 

 the same results as to the condition of the kidney, 

 but from the ureter having been divided and tied, 



c 2 



