104 



CHEMICAL EQUILIBRIA 



The figures for the two highest concentrations 

 are more uncertain than the others. The agree- 

 ment between the observed figures and the calculated 

 ones, which are evaluated on the assumption that 

 the concentration of the lysin is 286 times greater 

 in the blood-corpuscles than in the surrounding 

 salt -solution, may be regarded as extremely satis- 

 factory. 



I have determined the partition coefficient of 

 different substances between red blood-corpuscles 

 and an isotonic aqueous solution, in most cases 0-9 

 per cent NaCl-solution, but for the experiments with 

 silver nitrate 7-5 per cent cane-sugar solution. The 

 surrounding solution must be isotonic with, that is 

 possess the same osmotic pressure as, the red blood- 

 corpuscles, otherwise they may be haemolyzed by the 

 solution. The red blood-corpuscles take up more 

 of the investigated substances, all of which possess 

 haemolytic properties, than the surrounding solution, 

 therefore the partition coefficient, that is the propor- 

 tion of the concentration of the investigated substance 



