CHEMICAL EQUILIBRIA 103 



both phases, for instance a blood-corpuscle and the 

 surrounding fluid, then the concentration in the one 

 phase shall be in a constant proportion to that in 

 the other phase. This is even true if the substance 

 enters into compounds which contain or correspond 

 to just one molecule of the substance. For instance 

 a lysin, e.g. tetanolysin or vibriolysin, probably enters 

 into a compound with some proteid in the red blood- 

 corpuscles. If for the production of one molecule 

 of this compound precisely one molecule of the lysin 

 in the surrounding fluid is used up, then the concen- 

 tration of the lysin in the surrounding fluid and in 

 the red blood-corpuscle shall be in a constant pro- 

 portion. This occurs for vibriolysin according to 

 the following figures for solutions containing 9-84 cc. 

 of 0-9 per cent NaCl-solution, and 016 cc. of red 

 blood-corpuscles in emulsion. Different quantities 

 of vibriolysin were added (but always so that the 

 total volume was 10 cc.), and by haemolytic experi- 

 ments it was determined how much was taken up 

 by the red blood-corpuscles and how much remained 

 in the solution. The experiments carried out by 

 MADSEN and TERUUCHI and calculated by myself 

 gave the following results : 



[TABLE 



