LECTUEE 



LATER RESEARCHES THE COLLABORATION AND 

 MUTUAL RELATIONSHIPS OP THE DIGESTIVE 

 JUICES BILE AND SUCCUS ENTERICUS MOVE- 

 MENTS OF THE STOMACH PATHOLOGY AND EX- 

 PERIMENTAL THERAPEUTICS OF DIGESTION 

 THE METHOD OF EXPERIMENT IS THE ONLY 

 ONE ADEQUATE TO PRESENT-DAY MEDICAL RE- 

 QUIREMENTS. 



Later researches on the digestive glands -The physiology and psychology 

 of salivary secretion New method for the separate study of gastric secretion 

 The multiplicity of functions attributed to the bile is an indication of our 

 lack of knowledge of the physiology of this secretion Method of studying 

 the biliary secretion The entry of bile into the intestine is dependent on 

 the presence and the nature of the food The true digestive function of the 

 bile is to augment the activity of the ferments of pancreatic juice The 

 svccus enterieiis has also the same function A ferment of ferments, the 

 ENTEROKINASE Mechanical excitation effects a secretion of .wccvs en- 

 iericiis, but only of its watery constituents Pancreatic juice is a specific 

 excitant of the kinase The favouring influence of avccvs entcrlcus upon the 

 trypsin of pancreatic juice depends upon the transformation of the zymogen 

 into trypsin The amount of trypsin in the form of zymogen depends on the 

 nature of the diet The spleen and the pancreas The propulsion of food 

 along the digestive canal ; its functional adaptation thereto Experiments 

 on the movements by which the stomach is emptied of its contents The 

 passage of chyme into the intestine is regulated by impulses generated in 



* This lecture was delivered at the anniversary meeting of the Society 

 of Russkm Medical Men five years later than those preceding. It was also 

 dedicated to the memory of S. P. Botkin in the names of Professor Pawlow and 

 the following collaborateurs : J. 0. Lobassow, A. N. Wolkowitsch, J. C. Soborow, 

 J. C. Sawriew, A. A. Walt her, L. P>. Popielski, A. R. Krewer, G. G. Bruno, 

 N. N. Kladnizki, S. H. Wulfson, W. W. Nagorski, D. L. Glinski, N. P. Schepowal- 

 nikow, A. 8. Serdjukow, P. 0. Shirokich, E. A. Hanicke, and A. P. Sokolow. 

 The lecture was afterwards published as a separate pamphlet under the title, " The 

 Experimental Method An indispensable Requirement of Medical Research." 

 ( Translator.} 



