THE WORK OF THE DIGESTIVE GLANDS. 



7-0 

 8-0 



7-0 ., 

 2-0 .. 

 0-5 ., 



In the 1st hour, 82 - ."> c.e. 



1-0 



0-2 



0-8 ., 



"'I ,, 



(VO 



(1-2 



0-0 .. 



In the 2nd hour, 



c.c. 



Thereupon 250 c.c. water were poured in : no secretion followed for thirty 

 minutes. Then another 250 c.c. of the same hydrochloric acid solu- 

 tion were introduced and the quantities of juice recorded every ten 

 minutes : 



1*5 c.c. 

 13-5 

 15-0 

 10-0 

 13-0 

 15-0 



In the 1st hour, 74 - c.c. 



13-0 c.c, 

 l.VO 

 10-5 



y-0 ,. 



7'5 ,. 



io-r. 



In the 2nd hour, 65'5 c.c. 



3-D c.c. 

 0-2 

 Secretion stopped 



No particular difference in the exciting effect of various acids was 

 noticed. The acids investigated were phosphoric, citric, lactic and 

 acetic, in addition to the hydrochloric. 



The constancy and intensity of the acid influence stands out as 

 a very remarkable, indeed, an exceptional fact. The idea, therefore, 

 at once occurred to vis that we had discovered in acids the specific 

 excitant of the pancreatic gland, and simultaneously we remembered 

 that the contents of the stomach normally possess an acid reaction. 

 It, therefore, appeared to us that this acid reaction probably serves 

 as a connecting link between two neighbouring compartments of the 

 alimentary canal. But all these interesting and pregnant supposi- 

 tions had to be proved and established experimentally. In the first 

 place, the effects of increasing strengths of hydrochloric acid (from O'Oo 

 to 0-5 per cent.) were tried and with the following results : 



Into the stomach 250 c.c. of HC1 of the following strengths were 

 poured : 



