240 FRANK A. HARTMAN. 



In the second there were ninety-six on one side and eighty-one 

 on the other. The first was equivalent to four or five cells and 

 the last to eight cells. The chromosomes in these giant cells 

 seem to act normally, that is, they divide and pass to the poles 

 and maintain their individuality in every way, but the cell as 

 a whole fails to divide. 



In pathological mitosis the spindles are often multipolar and 

 the number of chromosomes passing to each pole is then very un- 

 equal, while in these giant germ cells the mitotic figure is always 

 bipolar and the number of chromosomes passing to each pole is 

 nearly the same. 



It may be that giant spermatozoa, formed from such cells as 

 these just described, are the cause of monstrosities when they 

 succeed in fertilizing an egg. 



