ACTION OF PICROTOXIXE 



233 



Fig. 216. Tracings from the gastrocnemius muscle of a frog injected with brucine. 



EXPERIMENT XXXVIII. 



Picrotoxine,* Chloretone. (Dog: Blood-pressure, Respira- 

 tion and Kidney, Spleen or Intestinal Loop Volume.) 



1. Dissolve three grams of chloretone in about eight 

 cubic centimeters of absolute alcohol. Then add water 

 until a slight precipitate starts to form. Then add a few 

 drops more of alcohol to dissolve the precipitate. Now 

 observe carefully the method of giving drugs to dogs il- 

 lustrated in Fig. 217. The dog for this dose of chloretone 



*Picrotoxine is not often used in medicine. 



