25-t EXPERIMENTAL PHARMACOLOGY 



2% sodium nitrate, 



2% sodium phosphate, 



2% sodium chloride, 



2% ammonium chloride, 



2% ammonium acetate. 



Arrange to observe the full action on urine secretion and 

 cautiously inject one-half cubic centimeter (or less) of the 

 solution in the burette. With great care gradually inject 

 more of the solution from time to time as rapidly as the 

 animal can tolerate it. What effect has this on the urine 

 floAv ? Continue the administration as long as satisfactory 

 results can be obtained. 



EXPERIMENT LI. 



Urea, S. A. Matthews' Solution, or Saline Diuretics. 

 (Rabbit or Cat: Diuresis.) 



1. Repeat the above experiment with a rabbit or cat (us- 

 ing two grams of urethane for an average sized animal, or 

 1.7 cubic centimeters per kilogram of paraldehyde for a 

 rabbit Edmunds) but after securing the normal rate of 

 urine flow begin to inject one of the following: 



A. Urea (5% solution). 



B. S. A, Mattheic's solution: 

 NaCl, 3.67 grams. 

 Na,S0 4 , 10.1 grams. 

 Sodium Citrate, 3.36 grams. 

 CaCL, 0.136 grams. 

 Water, 1000 c.c. 



C. Three per cent solution of any of the following: 

 Sodium sulphate. 



Sodium phosphate. 

 Sodium nitrate. 

 Ammonium nitrate. 



