296 



EXPERIMENTAL PHARMACOLOGY 



ter of adrenaline. Wait the blood circulates slowly. 

 What do yon observe ? How do yon explain it ? What 

 mechanical factors are concerned? A second contraction 



Fig. 264. Tracing shewing the action of local (Burrough . V," llcome and Co.) on 

 the blood-pressure and bronchioles in a spinal dog. The animal had received a dose of 

 pilocarpine a little while before this tracing begins and the bronchioles were partially 

 contracted (tonus) from the action of the pilocarpine which exercises a prolonged effect 

 on the broncho-constrictor nerve endings. 



of the bronchioles will likely come on as the effect of the 

 adrenaline passes off. Wait for this and give a second in- 

 jection of adrenaline. (If the first dose of pilocarpine was 



