382 



EXPERIMENTAL PHARMACOLOGY 



EXPERIMENT CVIII. 



Pituitrin, Ergamine, Adrenaline. (Dog, Cat, or Rabbit: 

 Uterine Contractions, Blood-pressure.) 



1. Cats are preferred for the experiment. Observe care- 

 fully the arrangement of the animal and the apparatus 



-Burette in 

 extjuguldr vein 



Burette in 

 femoral vein 



Bun sen i^ 

 burner 



Tube to 

 artificial 



respiration 

 machine 



Fig. 317. Arrangement of apparatus for recording contractions of the uterus in situ. 

 (The experiment is difficult and often yields unsatisfactory results.) A somewhat similar 

 arrangement may be used for recording intestinal contractions. 



shown in Fig. 317. The animal is given .3 to .4 gram per 

 kilogram of body weight of ehloretone (dissolved in alcohol) 

 by stomach tube. Artificial respiration may be given 

 throughout the experiment. Arrangements are made for 

 recording the blood-pressure (omit this if sufficient appara- 

 tus is not available), and injecting cannulas are connected 

 with one femoral vein and one external jugular. These con- 



