LYMPH FLOW PITUITEIN 387 



with levnlose solution (five or ten per cent). In small re- 

 peated doses (one-half or one cubic centimeter) several 

 cubic centimeters of the levulose solution are injected. Wait 

 then and see how the rate of lymph flow is affected. (How 

 is the lymph flow from the head affected? Is this rate of 

 flow maintained or does it decrease after a time!) 



After some time note the rate of lymph flow and adjust 

 all writing points. Observe the pupils and inject one cubic 

 centimeter of ergamine. Do you get satisfactory records? 

 If the dose was too small wait a while and inject a larger 

 one to get good results. How did the bladder respond? 

 How does this compare with pituitrin? 



Inject adrenaline and see how this affects the lymph flow, 

 bladder, pupil and respiration. 



With what other lymphogogues are you acquainted ? You 

 may try some of these on the animal if it is still in suitable 

 condition. Kill the animal with an injection of some of the 

 drugs you have. Always get a death record in such cases 

 and see which stops first, the heart or the respiration. 



How may drugs affect the rate of secretion or of flow of 

 lymph? How is the formation of lymph controlled? What 

 can you say about the innervation of the lymphatics ? HOAV 

 does atropine affect lymph secretion? 



EXPERIMENT CX. 



Pituitrin. (Frog: Capillary Circulation.) 



1. As in Experiment C, page 361, arrange a frog for ob- 

 serving the capillary circulation in the web of the foot (Fig. 

 305). Observe carefully (for comparison) the normal rate 

 of capillary flow and then inject one-half cubic centimeter 

 (or more) of pituitrin under the skin of the frog's back. 

 From moment to moment again observe the circulation in 

 the web and see if any change occurs. If you note a change 

 keep a careful watch on the animal from time to time for 



