ACTION OF LOBELHSTE 



327 



Fig. 288. Tracing showing the action of lobeline (two injections) on the bladder, 

 bronchioles and blood-pressure in a spinal dog which had previously received a sufficient 

 amount (135 mgs. ) of heroine to render the animal insusceptible to the specific action 

 of the drug on the bladder and bronchioles. Evidently here the first dose of lobeline 

 produced ganglionic paralysis as shown by failure of response to the second dose. 



