PEKFUSIOX OF THE KIDNEY 



345 



When a satisfactory record has been obtained examine 

 the temperature of the solution entering the kidney and if 

 necessary change the pressure of the perfusion fluid. (It 

 may be advisable to flush out the organ by temporarily 

 increasing the pressure considerably.) When everything 



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Fig. 299. Tracings made by the use of the apparatus shown in Fig. 298, showing 

 the action of sodium orthovanadate, barium chloride, and adrenaline on the volume of 

 an excised kidney from a dog. (For discussion see text. ) 



is again ready inject one or two cubic centimeters of 

 barium chloride solution (one-half per cent). Wait for the 

 drug to pass into the kidney. The circulation often be- 

 comes slow in organs thus perfused. Do you get a satisfac- 

 tory record ? Explain the action of the drugs studied. 



