416 



EXPERIMENTAL PHARMACOLOGY 



Eeplace the digitoxin in the burette and continue the re- 

 cords. Inject more digitoxin and strophanthin from time 

 to time and slowly bring on the action of the drugs. "\Vatch 

 that the animal does not die suddenly from some unknown 

 cause and the drugs be accepted as the cause of death. Ani- 



Detail of 

 rubber 



Qlass 



Bdnd to attach bowls to lobe of \\ver 



Tube to 

 , tambour 



Halleck. 



Fig. 335. Schematic illustration showing the principles involved in the construction 

 of Edmunds' liver oncometer. The two curved spoon-shaped pieces are made of dental 

 impression compound. This is a brownish substance (resembling sealing-wax) which softens 

 and becomes easily moulded with [he hands when placed in hot water for a while, but 

 hardens on cooling. Obtainable from dental supply houses. Thin flat rubber bags fit 

 inside the curved pieces and these bags rit just over the outside of the left lobe of the 

 exposed liver. Records are made by air transmission to a tambour. 



mals arranged for recording pulmonary blood-pressure 

 often do not live long and it is important to work rapidly 

 and accurately. Can you detect any evidence that the heart 

 has been especially stimulated or strengthened by the 

 drugs? Do you know of any other drugs previously studied 



