PHLORIDZIN, ADRENALINE, POTASSIUM IODIDE 457 



for the animal to die. After death pass a trocar into the 

 bladder (or catheterize) and draw off some urine. Test 

 this for albumen (nitric acid test) and for reducing' bodies 

 (Fehling's test). Put live cubic centimeters of urine in a 

 test tube and add a few drops of ferric chloride solution. 

 If you get a color reaction what does it mean? Put some 

 of the urine in a beaker and set it aside until next day to 

 observe any later changes in color. Open the stomach care- 

 fully (over a sink) and examine closely the condition of 

 the gastric mucosa. What would the stomach lining show 

 if sectioned and examined histologically f Do this if you 

 can. What conclusions can you draw? How is carbolic 

 acid excreted! What is the fate of the drug in the tissues? 

 (See Sollmann, Brown, Clarke: Journal American Medical 

 Association, 1906, March 17, and 1907, March 23; also Jour- 

 nal of Pharmacology, i, p. 409.) 



EXPERIMENT CLXI. 

 Phloridzin, Adrenaline. (Rabbit: Glycosuria.) 



1. Dissolve one-fourth gram of phloridzin in warm water, 

 and inject it subcutaneously into a rabbit. Obtain a sam- 

 ple of the urine at the end of two hours, by pressure on 

 the abdomen with the thumb or by passing a catheter, and 

 tost for sugar. If none is present wait some time longer 

 and again test the urine (Stewart). Glycosuria may also 

 be produced by injecting subcutaneously into a rabbit one 

 or two cubic centimeters of adrenaline (1:1000). The rab- 

 bits should be placed in a cage where the urine can be col- 

 lected. 



EXPERIMENT CLXII. 

 Potassium Iodide. (Student: Absorption, Excretion.) 



1. Take by mouth a capsule containing five grains of 

 potassium iodide. (Iodides have to be used with care in 

 cases of pulmonary phthisis.) 



