MICROBIAL DISEASES OF MAN AND ANIMALS. 585 



greatly by reason of excessive connective-tissue formation, and the greatly 

 thickened skin. 



Saccharomyces farciminosus is a yeast-like fungus, ovoid in shape and 3/u to 5/4 long 

 by 2.5ft to 3-5/z broad. This fungus grows slowly under artificial conditions on agar 

 and bouillon after inoculation with pus from an abscess. It reproduces by budding 

 and does not stain well by common laboratory stains. Claudius' method of staining 

 gives good results. 



Cases should be isolated and stables disinfected by the free use of very 

 strong disinfectants as this Saccharomyces is not easily killed by ordinary 

 disinfecting solutions. 



Another mycotic organism has more recently been reported* in the 

 United States as causing a lymphangitis very similar clinically to the 

 lymphangitis caused by Saccharomyces farciminosus. Cases supposed to 

 have been plain cases of the Saccharomyces form showed on laboratory 

 examination a Sporothrix acting as the direct cause. These workers* 

 reproduced cases by inoculation and recovered an organism differing very 

 materially from Saccharomyces farciminosus. The case history and le- 

 sions produced parallel very closely those produced by the Saccharomyces. 

 This Sporothrix seems to have great vitality, remaining virulent in dried 

 pus at a temperature of 7 for three months or more. 



The same organism has been recovered from similar lesions of the 

 human where it was apparently acting as the direct exciting cause. If 

 this be confirmed, we have two very different organisms each capable 

 of producing a similar mycotic lymphangitis. 



DISEASES CAUSED BY BACTERIA.f 



BOTRYOMYCOSIS.J 



In view of recent information, " botryomycosis " should be considered 

 as a rather general term and as not referring to a specific bacterial disease. 

 The name has been given to various lesions of similar character involving 

 especially connective tissue. We have in this disease a type of closed 

 abscesses with fibrous walls. These abscesses involve especially sub- 



* Sporothrix and Epizootic Lymphangitis, Page, Frothingham, and Paige. Journal of Med- 

 ical Research, Volume XXIII, No. i. Previously reported by Shenck, Hektoen, and others for 

 the human. 



t Arranged alphabetically under each, of the following families: Coccacece (Micrococcus, 

 Streptococcus), Bacteriaceiz (Bacterium, Bacillus, Pseudomonas), Spirtllaceze (Microspira). 



J Prepared by M. H. Reynolds. 



