146 BACTERIA IN RELATION TO DISEASE 



The relations between the cellular elements of the body and the 

 invading bacteria are probably similar in all cases. Some bacteria are intra- 

 cellular, that is to say, they live in the cell-substance, but the majority 

 are intercellular, the destruction of the cells being a secondary process. 

 The bacteria multiply in the secretions and exudations of the diseased 

 tissue, pushing themselves in between the cells and into the spaces caused 

 by the pathological softening and loosening of connective tissue. 



