NOTES 173 



45. (p. 73). WITTLIN, Centralbl. f. Bakt., 2. Abt. vol. ii, i8<6, p. 676. 



46. (p- 73)- CERTES, De 1'action des hautes pressions sur les phenomenes de la putrd- 



faction et sur la vitalite dcs microorganismes d'eau douce et d'eau de mcr. 

 Comptes rendus, 1884, vol. xcix. p. 385 (reference in Bot. Zeit. 1885). 



47. (pp. 73, 75). The literature concerning bacteria in their relation to temperature is 



enormous, since almost every work dealing with a new species describes its 

 behaviour to heat. The foundations of our knowledge of the subject were laid 

 by COHN (Untersuch. ii. Bakterien iv, in Beitr. z. Biol. vol. ii, 1876). He based 

 his work on that of the older investigators in physiology and the problem of 

 spontaneous generation, and showed first that the spores of the hay-bacillus 

 resisted boiling. ROBERT KOCH introduced the methods and results of plant 

 physiology into medical bacteriology, Beitr. z. Biol. vol. ii. 



48. (p. 74). MIQUEL, P., Annuaires de 1'observatoire de Montsouris 1881, and Mono- 



graphic d'un bacille vivant au dela de 70 centigrades (Bac. thermophilus], in 

 Annales de Micrographie i, 1888 (references in Centralbl. f. Bakt. vol. v, 1889) ; 

 also GLOBIG, Zeitschrift fur Hygiene, vol. iii, 1888, and RABINOWITSCH, ibid, 

 vol. xx. 



49. (p. 75). For the lowest artificial temperatures and their effect upon organisms of all 



kinds, see WELTER, Die tiefen Temperaturen, ihre kiinstliche Erzeugung, etc., 

 Krefeld 1895. 



50. (p. 77). Experiments innumerable have been made on the power of bacteria to resist 



desiccation ; here again the fundamental facts were given by COHN in the 

 Beitr. z. Biol. ; see also EIDAM, Die Einwirkung verschiedener Temperaturen 

 und des Eintrocknens auf die Entwicklung von Bacterium termo, Beitr. z. Biol. 

 vol. i, 1875. 



51. (p. 78). STAHL, Zur Biologic der Myxomyceten, Bot. Zeit. 1884 (p. 165, Tropho- 



tropism). 



52. (p. 78). PFEFFER, W., Lokomotorische Richtungsbewegungen durch chemische Reize, 



Untersuch. a. d. bot. Institut Tubingen, vol. i, 1884, and Ueber chemotaktische 

 Bewegungen von Bakterien, Flagellaten und Volvocineen, ibid. vol. ii, 1888. 

 In these two classical works will be found also a full discussion of Weber's 

 law and Chemotaxis. 



53. (p. So). For chemotaxis of leucocytes see : M ASSART and BORDET, Recherches sur 



Pirritabilitd des leucocytes, Socie"te royale des sc. nat. de Bruxelles, 1890; 

 GABRITSCHEWSKY in the Annales de 1'Inst. Pasteur, 1890; BUCHNER, Berl. klin. 

 Wochenschr. 1890 ; also the description given by RlEDER, Beitrage zur 

 Kenntnis der Leukocytose, Leipzig 1892. 



54. (pp. 81, 82, 83). On chemical disinfection abundant information will be found in medical 



literature ; the subject is treated very fully by BEHRING, Bekampfung der 

 Infektionskrankheiten, 1894. The fundamental principles were given by 

 R. KOCH in Ueber Desinfektion, Mitt, aus dem kaiserl. Gesundheitsamte, 

 vol. i, 1 88 1 ; see also GEPPERT, Die Wirkung des Sublimates auf Milzbrand- 

 sporen, Deutsche med. Woch. vol. xvii, 1890; YERSIN, De 1'action de quelques 

 antiseptiques et de la chaleur sur le bacille de la tuberculose, Annales de 1'Inst. 

 Pasteur, 1888. 



55. (pp. 83, 85, 86). PAUL and KRONIG, Ueber das Verhalten der Bakterien zu chemischen 



Reagentien, Zeitschr. f. physik. Chemie, vol. xxi, 1896, and Miinchener mediz. 

 Wochenschr. 1897 ; also Die chemischen Grundlagen der Lehre von der Gift- 



