22 



METABOLISM IN SEVERE DIABETES. 



The urinary record is given in table 9. The records for October 1911 

 show probably a far nearer approach to the patient's average urinary excretion 

 than the quantities recorded in the hospital. During his stay in the hospital 

 the amount of urine excreted was low, owing to the diarrhea, and possibly 

 because of restrictions in diet, while in October 1911 he was absolutely his 

 own master. The low acidosis is notable and can in a measure be explained by 

 the liberal allowance of carbohydrates in the diet. The reaction of the urine 

 was acid throughout the whole period of observation, and there was but a 

 slight trace of albumen. 



EXPERIMENTS WITH CASE I. 



Two experiments were reported with this subject in the previous publica- 

 tion; one additional experiment is reported here, for which the bed calorimeter 

 was used. The vital statistics for this subject are as follows: 



Date of birth, February 2, 1886; height, 176 cm.; body-weight without 

 clothing during experiment, 40.0 kilos. 



Table 10. Measurements of metabolism Calorimeter experiment No. I\. 



1 Subject drank a cup of clear coffee without sugar at 7" 50 ra a.m. 



- Carbon dioxide eliminated per kilogram per minute, 4.33 c.c; oxygen absorbed per kilogram per minute, 6.03 c.c. 



Calorimeter Experiment No. II. 



Date, February 23, 1911. Body- weight without clothing, 40.0 kilos. 



Previous to this experiment the subject had taken no food since the even- 

 ing meal of the day before, with the exception of a cupful of clear coffee, with- 

 out sugar, at 7 h 50 m a. m. He arrived at the laboratory at 8 h 05 m a. m., and 

 entered the bed calorimeter in readiness for the experiment at 8 h 53 m a. m. 

 The experiment began at 9 h 32 m a. m., continuing for two 45-minute periods, 



Table 11. Statistics of urine Calorimeter experiment No. I\. 



Subject drank a cup of clear coffee at 7 h 50 m a.m., without sugar. 



ending at ll h 02 m a. m. The subject telephoned twice during the experiment, 

 once at the beginning of the first period and again in the second period, at 

 10 h 40 m a. m., when he asked how much longer he would have to stay in the 

 calorimeter. Aside from this he lay very quietly. As the chair calorimeter 

 had been used in the previous experiments with this subject, this was his first 

 experience with the bed calorimeter. He said that he did not find the experi- 

 ment especially irksome, except that lying still in one position so long made his 



