32 



METABOLISM IN SEVERE DIABETES. 



reported as being restless, opening his mouth once and raising his hand to his 

 face. Before coming to the laboratory the subject urinated at 5 a. m., and 

 after the experiment was over he urinated at 8 h 50 m a. m. The carbon dioxide 

 eliminated per minute was 181 c.c, and per kilogram per minute 5.57 c.c. The 

 oxygen absorbed per minute was 237 c.c. per minute, and per kilogram per 

 minute, 7.29 c.c. The respiratory quotient was 0.76. During the experi- 

 mental period the pulse-rate averaged 73 and the respiration-rate, 17. The 

 urine collected between 5 a. m. and 8 h 50 m a. m. amounted to 145 c.c. and con- 

 tained 0.67 gram of nitrogen and 7.1 grams of sugar. 



Calorimeter Experiment No. N2. 



Date, December 1, 1910. Body-weight without clothing, 31.2 kilos. 



For this experiment, the subject came to the laboratory without break- 

 fast at 7 h 05 m a. m., and entered the bed calorimeter at 7 h 17 m a. m. The 

 experiment began at 8 h 04 m a. m., and continued for three 45-minute periods, 

 ending at 10 h 19 m a. m. The pulse and respiration rates were obtained by the 

 usual methods, but no records of the body-temperature were made. The sub- 

 ject was very quiet, lying on his back and reading throughout the whole experi- 

 ment. Two samples of the alveolar air were taken both before and after the 

 experiment. Before coming to the laboratory, the subject urinated at 6 h 45 m 

 a.m., and again after the experiment at 10 h 28 m a.m. The records of the 

 experiment are given in tables 22 and 25. 



Table 22. Measurements of metabolism Calorimeter experiment No. N 2. 



1 One record at 10 1 ' 03 m a.m. 



2 Carbon dioxide eliminated per kilogram per minute, 4.26 c.c; oxygen absorbed per kilogram per minute, 5.74 c.c. 



Calorimeter Experiment No. N3. 



Date, December 2, 1910. Body-weight without clothing, 30.9 kilos. 



On the morning of the experiment the subject ate a breakfast consisting of 

 300 grams of cooked oatmeal and came to the laboratory at 7 h 55 m a. m. At 

 8 h 10 m a. m. he entered the respiration chamber of the bed calorimeter; the 

 experiment began at 8 h 48 m a. m. and continued for two 45-minute periods and 

 one 53-minute period, ending at ll h ll m a. m. In the first period he lay very 

 quietly on his back, reading, but did not read in the second period and moved 

 slightly two or three times; he seemed to be asleep near the end of the period. 

 At the beginning of the third period he was asleep, but soon awoke and read for 

 a short time, then lay quietly without reading. According to the observer's 

 record, the subject moved considerably more in this period than in the two pre- 

 ceding, and it was necessary to extend the period 8 minutes in order to obtain 

 satisfactory temperature equilibrium at the end. Samples of alveolar air were 

 taken before and after the experiment. The subject urinated at 7 a. m. before 

 coming to the laboratory and again at ll h 26 m a. m. after the experiment was 

 over. The records for the experiment are given in tables 23 and 25. 



