STATISTICS OF EXPERIMENTS. 



61 



used to obtain records of the respiration rate and the major movements. At 

 9 h 20 m a. m. the subject drank 60 cc. of water. After coming to the laboratory 

 in the morning he urinated at 7 h 28 m a. m., also during the experiment, at 

 9 h 15 m a. m., and after the experiment was over, at 10 h 40 m a. m. The records 

 are given in tables 68 and 69. 



Table 68. Measurements of metabolism Calorimeter experiment No. R4- 



1 Carbon dioxide eliminated per kilogram per minute, 3.51 c.c : oxygen absorbed per kilogram per minute, 4.90 c.c. 



Table 69. Statistics of urine Calorimeter experiment No. R4- 



Date and period. 



May 12, 1911: 



7 h 2S m a.m 



7 28 a.m. to 9 h 15 ra a.m 

 9 15 a.m. 10 40 a.m 



Volume. 



Specific 

 gravity. 



c.c. 

 115 

 251 



182 



1.026 

 1.025 

 1.024 



Total 

 nitrogen. 



Sugar. 



gms. 



0.55 



1.19 



.87 



gms. 

 '2.8 

 5.9 

 3.9 



CASE S. 

 DESCRIPTION OF THE CASE. 



Male; born 1853; married; merchant; onset of diabetes in 1899; came 

 under our observation May 12, 1910; died in coma October 19, 1910. 



Family history. No history of diabetes mellitus. Father died at 87; 

 mother of cancer; one brother of liver trouble; one brother and one sister in 

 infancy; one son 33 years old, well. 



Past history. Health neither very poor nor very good. Measles, mumps, 

 herpes, hemorrhoids. 



General history of case. The diabetes was first apparent in 1899 with 

 malaise. The greatest quantity of sugar noted was 3.5 per cent, while the 

 greatest volume of urine was 2400 c.c. The general condition of the patient 

 was excellent. The patient was under observation for only a short period of 

 time. Death occurred some 5 months afterwards while the patient was travel- 

 ing, and was considered due to coma. 



Physical examination. Greatest weight, April 1901, was 71.1 kilos, with- 

 out clothes; May 13, 1910, 57.6 kilos, undressed. Height, 177 cm.; tour de 

 taille 76 cm.; pupils equal, reacted; knee-jerk normal; blood-pressure 120; 

 pulse 72. Nothing abnormal noted about the heart and lungs. Liver extended 

 2 fingers' breadth below costal margin. Spleen extended to the costal margin 

 and was hard. 



Urine data. The urinary records of the case are given in table 70. 

 Throughout the observation of the urine the reaction in all cases was acid, and 

 the slightest possible trace of albumen was present on every day except May 

 16-17. On all days of the observation, 8 grams of sodium bicarbonate were 

 given. 



