STATISTICS OF EXPERIMENTS. 



63 



Respiration Experiment No. S2. 



Date, May 21, 1910. Body-weight without clothing, 58 kilos. 



The subject came to the laboratory after eating at the hospital a break- 

 fast of approximately 250 gms. of cooked oatmeal between 7 h 30 m a. m. and 

 7 h 45 m a. m. He lay down upon the couch at 8 h 10 m a. m., and the experiment 

 began at 8 h 16 m a. m., continuing for four periods, 11 to 12 minutes long, with 

 intermissions of 12 to 15 minutes. Both pneumographs were used. The 

 subject urinated at 7 h 45 m a. m., before the experiment, and again after the 

 experiment, at 10 a. m. The data are given in table 72. 



Table 72. Results of respiration experiment No. S2. 



1 Subject ate oatmeal for breakfast between 7 h 30 and 7 h 45 a.m. 



2 Carbon dioxide eliminated per kilogram per minute, 2.78 c.c; oxygen absorbed per kilogram per minute, 3.69 c.c. 



The urine collected between 7 h 45 m and 10 a.m. amounted to 245 c.c. and contained 1.04 gms. nitrogen and 



10.2 gms. sugar. 



In order to compare his metabolism with that of a normal subject after 

 eating oatmeal, an experiment was made with another subject who had eaten 

 434 gms. of cooked oatmeal. The time intervening between the ingestion of 

 the oatmeal and the beginning of the experiment was the same as in the experi- 

 ment with the diabetic. The respiratory quotients obtained with the normal 

 subject were 0.806, 0.807, 0.854, and 0.780, respectively. 



CASE T. 



DESCRIPTION OF THE CASE. 



Male; born 1867; married; farmer; onset of diabetes in September 1908; 

 diagnosed November 1908; came under our observation December 5, 1910; 

 died in coma March 5, 1911. 



Family history. No history of diabetes mellitus. Father died at 77 

 years of heart disease; mother at 63 years of cancer; wife and six children well; 

 one child died of heart disease. 



Past history. Measles, mumps, whooping-cough, scarlet fever. 



General history of case. September 1908, there were polydipsia and poly- 

 uria, with loss of weight for a month previous to the diagnosis in November 

 1908. The chief symptom was weakness. Carbuncles and boils developed 

 in October 1910, and the patient also suffered from constipation. The diet 

 was at no time strict, as the feebleness of the patient, his inability to bear 

 sodium bicarbonate well, and the severity of the acidosis made restrictions of 

 diet appear impracticable. The patient failed to respond to diet, and died in 

 coma March 5, 1911, shortly after returning home. 



Physical examination. Greatest weight without clothing, 71.2 kilos.; 

 normal weight without clothing, 67.6 kilos.; weight December 5, 1910, 52.7 

 kilos, without clothing. Height, 180 cm. Pupils equal and reacted. Knee- 

 jerk normal. No edema. Lungs and heart normal. Pulse-rate, 72. There 

 were numerous boils and ulcers, some of which were partially healed, over the 

 clavicle, neck, arms, and back a truly pitiable sight. The breath had an 

 acetone odor. 



