78 



METABOLISM IN SEVERE DIABETES. 



EXPERIMENTS WITH CASE W. 



Two respiration experiments were made with this subject, in both of 

 which she fasted. The vital statistics were as follows: 



Date of birth, June 1, 1892; height, 161 cm.; range of body-weight 

 without clothing during experiments, 58.9 to 60.1 kilos. 



Respiration Experiment No. Wl. 



Date, May 13, 1910. Body-weight without clothing, 60.1 kilos. 



The subject came to the laboratory fasting at 7 h 45 m a. m., and lay down 

 upon the couch at 7 h 55 m a. in. The experiment began at 8 h 07 m a. m., con- 

 tinuing for four periods of 10 to 11 minutes each, with intermissions of 10 to 14 

 minutes. The subject was nervous throughout the whole experiment, espe- 

 cially in the last period; the respiration was consequently irregular. At the 

 close of the second period she said that her nose felt as if it were bleeding. Just 

 after the beginning of the third period she opened her mouth. After the experi- 

 ment was over the subject felt a little faint. She seemed to breathe easily 

 through the nose, and but for the nervousness was a very good subject. The 

 records of the experiment are given in table 97. 



Table 97. Results of respiration experiment No. W 1. 



'Carbon dioxide eliminated per kilogram per minute, 2.78 c.c; oxygen absorbed per kilogram per 

 minute, 3.91 c.c. The urine collected between 7 and 10 h 10 m a.m. amounted to 197 c.c. and 

 contained 0.94 gm. nitrogen and 1.6 gms. sugar. 



Respiration Experiment No. W2. 



Date, May 24, 1910. Body-weight without clothing, 58.9 kilos. 



This was also a fasting experiment, the subject having taken no food since 

 the evening meal of the day before. She arrived at the laboratory at 8 h 15 m 

 a. m., lay down on the couch at 8 h 30 m a. m., and the experiment began at 

 8 h 43 m a. m., continuing for three 10-minute periods, with intermissions of 11 

 to 14 minutes. She was not nearly so nervous as in the previous experiment, 

 but as the periods continued became more restless, and at the close of the last 

 period felt faint. The results of the experiment are given in table 98. 



Table 98. Results of respiration experiment No. W2. 



1 Carbon dioxide eliminated per kilogram per minute, 2.72 c.c; oxygen absorbed per kilogram per minute, 3.62 c.c. 

 The urine collected between 7 and 9 h 45 m a.m. amounted to 162 c.c. and contained 0.57 gm. nitrogen and 0.1 gm. sugar. 



