82 



METABOLISM IN SEVERE DIABETES. 



12 h 18 m p. m. Near the end of the first period the subject was asleep, waking 

 just after the beginning of the second period. He telephoned once in each 

 period. The subject urinated before coming to the laboratory at 7 a. m., and 

 three times during the experiment, i. e., at 9 h 28 m a. m., 10' 1 32 m a. m., and 

 1 1 h 35 m a. in., also at 12 h 25 m p. m., after the experiment was over. He drank 

 no water. The records of the experiment are given in tables 102 and 103. 



Respiration Experiment No. X3. 



Date, March 17, 1910. Body-weight without clothing, 64.6 kilos. 



On the experimental day the subject drank a cupful of coffee before com- 

 ing to the laboratory, but ate no breakfast. He reached the laboratory at 

 7 h 40 m a. m., lay down on the couch at 7 h 45 m a. m., and the experiment began 

 at 8 h 58 m a. m. The three periods ranged from 12 to 15 minutes in length, with 

 intermissions from 8 to 10 minutes, the last period ending at 9 h 56 m a. m. 

 After the experiment began the subject breathed slower and possibly deeper 

 than he had previously. In the second period he took several very deep 

 breaths. In this period, also, there was a slight leak in the nosepiece, and a 

 new nosepiece was accordingly used for the next period. Immediately after 

 the experiment was over the subject urinated at 9 h 56 m a. m., the last period 

 being shortened on account of the pressure of urine. The records of the experi- 

 ment are given in tables 104 and 106. 



Table 104. Results of respiration experiment No. X3. 



1 Subject drank a cup of coffee about If hours before experiment began. 



2 Carbon dioxide eliminated per kilogram per minute, 2.82 c.c; oxygen absorbed per kilogram per minute, 3.79 c.c. 



Calorimeter Experiment No. X4. 



Date, March 17, 1910. Body-weight without clothing, 64.6 kilos. 



This experiment was preceded by a five-period respiration experiment 

 (experiment No. X3). The subject drank a cupful of coffee on the morning 

 of the experimental day, but aside from this took no food after the evening 

 meal of the day before. He entered the chair calorimeter at 10 h 08 m a. m.; 

 the experiment began at 10 h 45 m a. m., continued for three 1-hour periods, 

 and ended at l h 45 ra p. m. The rectal thermometer was not used, but the 



Table 105. Measurements of metabolism Calorimeter experiment No. X4- 



1 Carbon dioxide eliminated per kilogram per minute, 2.93 c.c.; oxygen absorbed per kilogram per minute, 3.62 c.c. 



