126 METABOLISM IN SEVERE DIABETES. 



tity of carbohydrates in the diet. Inasmuch as this paper dealt especially 

 with the character and not with the amount of the metabolism, practically no 

 reference was made to the significant fact that apparently the lower the amount 

 of carbohydrates in the diet, the higher the metabolism. It is the purpose of 

 the following section of this discussion to state the details of these experiments 

 and to discuss the results. 



EXPERIMENTS WITH H. L. H. 



The study made with this subject included four experiments, all with the 

 respiration apparatus. Three of these were made with the carbohydrate-free 

 diet; the fourth followed normal diet. The special diet was begun on Sep- 

 tember 6, 1911, but the plan to study the respiratory exchange was not devel- 

 oped until the next day, so that the first respiration experiment was made on 

 September 7, 1911. The experiment on normal diet was therefore delayed 

 until the second day after the discontinuance of the carbohydrate-free diet. 

 The vital statistics for this subject are as follows: 



Date of birth, March 26, 1887; height, 172 centimeters; body-weight with- 

 out clothing during experiments, 60.2 kilos. 



STATISTICS OF EXPERIMENTS WITH H. L. H. 

 Respiration Experiment No. 1. 



Date, September 7, 1911. Body-weight without clothing, 60.2 kilos. 



The last meal preceding the beginning of the carbohydrate-free diet was 

 taken at 12 h 30 m p. m., September 5, and consisted of beef stew with vegetables 

 and bread and butter. The subject fasted the remainder of the day. On the 

 day preceding the first experiment he took for his breakfast eggs and beef tea; 

 for dinner, sardines and cheese; and for supper, pork chops. Samples of the 

 alveolar air were taken at 2 h 56 m and 3 h 52 m p. m. on this day. 



On the experimental day the subject came to the laboratory fasting; the 

 experiment began at 8 h 50 m a. m., continued for three 15-minute periods, with 

 intermissions of 19 and 11 minutes respectively, and ended at 9 h 55 m a. m. 

 The pulse-rate ranged from 80 to 88. The results of the experiment are given 

 in table 135. After the experiment was over the subject ate for his breakfast 

 at 10 a. m. soft-boiled eggs with butter; also took pepsin gum. For his dinner, 

 at 3 h 30 m p. m., he again took soft-boiled eggs with butter, while for his supper 

 he ate fried ham with a little butter. 



Respiration Experiment No. 2. 



Date, September 8, 1911. Body-weight without clothing, 60.2 kilos, 

 (assumed). 



At 8 a. m. on the experimental day the subject took a few sips of coffee, a 

 piece of pepsin gum, and a little lemon juice. The experiment began at 9 h 25 m 

 a. m., continued for three 15-minute periods with intermissions of 11 and 9 

 minutes each, and ended at 10 h 30 m a. m. The pulse-rate ranged from 72 to 

 80. The food taken by the subject throughout the day consisted of a break- 

 fast of lamb chops at 10 h 30 m a. m., a dinner of sardines at 2 h 30 m p. m., and a 

 supper of beefsteak at 8 p. m.. Samples of the alveolar air were taken on this 

 day. The results of the experiment are given in table 135. 



