OVARIAN GRAFTING IN ANIMALS OTHER THAN MAN. 5 



kept as control. In the operations the ovary of a black pullet was exchanged 

 with that of a white one. Six months after the operation the birds, which 

 had now beg'im to lay, were mated, with the following - results in chicks or 

 foetuses: 



1 . The control black hen mated with a black cock produced thirteen black 

 chicks with light breasts and throats. 



2. Black hen B 2, which had received an ovary from a white pullet and 

 was mated with a white cock, produced nine white chicks and eleven white 

 ones having black spots on heads, wings, or backs. 



3. Black hen B3, which had received an ovary from a white pullet and 

 was mated with a black cock, produced four ordinary black chicks (with light 

 under surfaces) and two chicks described as being "black with white legs." 



4. The control white hen mated with a white cock produced eighteen 

 white chicks. 



5. White hen W 2, which had received an ovary from a black pullet and 

 was mated with a white cock, produced three white chicks, one chick white 

 with black spots, and one ordinary black. 



6. White hen W3, which had received an ovary from a black pullet and 

 was mated with a black cock, produced twelve white chicks spotted with 

 white on head, wings, or back. 



The conclusions to be drawn from these observations will be discussed 

 elsewhere in this paper. 



Magnus (1907) transferred the ovaries from an albino to a black rabbit 

 with apparent success. The black rabbit was mated with an albino male 

 five months after the operation and a month later bore two young, one 

 black and the other an albino. Two months later she died pregnant, and 

 in the uterus were found two dark-colored embryos and five light-red ones 

 supposed to be albinos. No ovary was found on one side of the body, but 

 on the other side was a well-developed and functional ovary bearing corpora 

 lutea. Magnus supposes that all the embryos produced were derived from 

 eggs liberated by the transplanted ovary, but in view of our own experience 

 we are inclined to question this interpretation. 



Ten other rabbits similarly grafted by Magnus produced no young, though 

 three of them gave indications by their sexual activity that they contained 

 living ovarian tissue. 



Among other authors who have reported successful results with homo- 

 plastic grafting in animals may be mentioned: Schaus, Basso, Mauclaire, 

 McCone, and Lukaschewitsch. 



McCone gives the case of the birth of five well-formed offspring in a rab- 

 bit from the grafted ovary of another rabbit, but the evidence that the func- 

 tioning ovary was an introduced ovary is far from complete. Pregnancy 

 took place four months after complete castration and transplantation from 

 another member of the same species. The other authors report no young. 



