318 Influence of Inanition on Metabolism. 



experiment No. 68, no records of the pulse were made. But two records per 

 day were made in experiment No. 69, and these showed general uniformity of 

 the pulse rate from day to day, although the rate was somewhat higher on the 

 last day than on the first. In the food experiment No. 70, immediately follow- 

 ing fasting experiment No. 69, only two observations were made, both on the 

 second day. The two records show an increase of about 25 beats per minute 

 over those of experiment No. 69. The pulse rates were taken more frequently 

 in the series of experiments with S. A. B. than in Nos. 69 and 70. In experi- 

 ment No. 71, the rate steadily diminished during the four days of the fast. 

 During the following day (experiment No. 72) food was ingested and there 

 was a noticeable increase over the rate of the previous day. 



In experiment No. 73 the pulse rate continually decreased on each of the 

 5 days of the fast. After the ingestion of food (experiment No. 74) the 

 pulse rate increased materially on the first day, fell off slightly on the second, 

 and on the third day regained the rate of the first. 



In the 7-day experiment (No. 75) the pulse increased on the second day, 

 but continually diminished on the succeeding 6 days of the experiment. After 

 the ingestion of food (experiment No. 76) the pulse increased materially and 

 Avas highest on the third day. Contrary to previous experience with this 

 subject, in experiment No. 77, the pulse rate steadily increased for the 4 

 days of the fast, being highest on the last day. 



In the series of 2-day experiments with different subjects, in all except 

 experiment No. 89 the pulse rate increased on the second day. The rate 

 during this last experiment remained about the same on both days. The pulse 

 rate was usually lower during the night than during the day. Excepting the 

 observations during the day itself, and comparing only those during the night 

 it is seen that the pulse rate steadily increased during the 3 nights 21 of the 

 experiments. In a few instances the records for pulse rate are defective during 

 the preliminary nights and hence these can not be compared. But the increase 

 of pulse on the 3 nights is strikingly evident in experiments Nos. 80, 82, 83, 

 and 85, though it remained practically the same on all 3 nights of experiment 

 No. 89. 



An examination of the records for each experiment shows marked, and 

 frequently, sudden changes in the pulse rate. In the large majority of 

 instances the sudden increases in pulse can be accounted for by some body 

 movement immediately preceding them, such as going to the food aperture, 

 taking the strength tests, or changing from the reclining to the sitting or 

 standing positions. In a number of instances, however, the marked fluctuations 

 are not so readily explainable, and it seems not at all impossible that we have 



21 It will be remembered that the subject entered the chamber on the evening 

 before the experiment proper began. Hence there are 3 nights and 2 days in each 

 experiment. 



