462 



Influence of Inanition on Metabolism. 



of body-weight was observed on the first day of the fasr. A proper interpre- 

 tation of these fluctuations in the katabolism of fat can not be made without a 

 comparison of the amounts of glycogen which were simultaneously katabolized. 

 The large amount of fat drawn upon by the body to support its vital func- 

 tions is of special interest in connection with the question of acidosis during 

 fasts. This observation is wholly in accord with the modern conceptions 

 regarding the formation of organic acids from fat. 



Table 227. Fat katabolized in metabolism experiments without food. 



Experi- 

 ment 

 num- 

 ber. 



Subject and duration of 

 experiment. 



First day. 



o 



5 * 



U CS 



Ph 



Second day 



o 



be 



Ph 



Third day. 



o 



I to 



CO -.-t 



Mrs 



4).Q 

 Ph 



Fourth day 



o 



to 



TO -h 

 t. 4) 



5 ' 



b O 



Ph 



59.. 

 68.. 

 69.. 

 71.. 

 73.. 

 75.. 

 77.. 

 79.. 

 80.. 

 81.. 

 82.. 

 83.. 

 85.. 

 89.. 



B. F. 

 A. L. 

 A. L. 



S. A. 

 S. A. 

 S. A. 

 S. A. 

 H. E. 



C. R. 

 A. H. 

 H. C. 

 H. R. 

 N. M. 



D. W. 



D., Dec. 

 L., Apr. 

 L., Dec. 

 B., Jan. 

 B., Jan. 

 B., Mar. 

 B., Apr. 

 S., Oct. 

 T., Oct. 

 M., Nov. 

 K., Nov. 

 D., Dec. 

 P., Dec. 

 , Jan. 



18 to 



27 to 

 16 to 



7 to 



28 to 



4 to 



8 to 

 13 to 

 27 to 

 21 to 

 24 to 



5 to 



9 to 

 10 to 



20, 1903. 

 28, 1904. 

 19, 1904. 

 10, 1905. 

 Feb. 1,1905 



10, 1905.. 



11, 1905 . 

 14, 1905.. 

 28, 1905. . 

 22, 1905 . 

 25, 1905.. 



6, 1905.. 



10, 1905 . 



11, 1906.. 



Gms. 

 150.7 

 145.1 

 134.9 

 116.5 

 106.6 

 126.4 

 135.0 

 132.6 

 141.6 

 146.9 

 140.1 

 156.2 

 127.4 

 131.8 



Gins. 

 2.25 

 2.01 

 1.84 

 2.02 

 1.82 

 2.12 

 2.20 

 2.34 

 2.07 

 2.39 

 1.97 

 2.82 

 1.91 

 1.68 



Gms. 

 156.6 

 160.6 

 174.3 

 152.3 

 151.7 

 147 5 

 171.9 

 158.2 

 190.1 

 161.2 

 203.6 

 143.9 

 168.0 

 182.6 



Gms. 

 2.37 

 2.27 

 2.40 

 2.68 

 2.63 

 2.49 

 2.85 

 2.85 

 2.85 

 2.67 

 2.90 

 2.63 

 2.56 

 2.37 



Gms. 

 183.4 



161.7 

 142.9 

 152.6 

 153.0 



137.7 



Gm 

 2.80 



Average . 



135.1 



2.10 



165.9 2.61 



155.2 



2.54 



Gms. 



Gms. 



169.2 

 133.0 

 139 . 2 

 144.7 

 149.9 



2.37 

 2.39 

 2.48 

 2.51 

 2.60 



147.2 



2.47 



Experi- 

 ment 

 num- 

 ber. 



Subject and duration of 

 experiment. 



Sixth day. 



Seventh day, 



CO 



o 



H 



to 



03-^ 

 - ID 



.2 ' 



M-Z3 

 >*8 

 Ph 



o 



5 to 



U 4) 



of 



>. 

 Mrs 



Ph 



73... 

 75 . . . 



S.A.B., Jan. 28 to Feb. 1, 1905 

 S.A.B., Mar. 4 to 10, 1905 . . . 



Average 



Gms. 

 148.1 

 144.7 



146.4 



Gms. 

 2.68 

 2.54 



2.61 



Gms. 



129.8 



Gms. 



2.30 



129.8 



2.30 



Gms. 

 132.5 



Gms. 



2.36 



132.5 2.36 



There is good reason to suppose that the slight muscular activity exhibited 

 by the subjects of these experiments could not have had any marked influence 

 on the protein katabolism. Even slight variations in muscular activity, how- 

 ever, have considerable effect upon the amount of fat katabolized, hence it is 



