4G4 



Influence of Inanition on Metabolism. 



The computations are based on the loss to the body of nitrogen, carbon, hydro- 

 gen, and oxygen, the elementary analyses furnishing the data whereby these 

 losses are determined. 



The amounts of glycogen katabolized per day together with the quantities 

 per kilogram of body-weight are recorded in table 228. 



Table 228. Glycogen katabolized in metabolism experiments without food. 



Ex- 

 peri- 

 ment 

 num- 

 ber. 



Subject and duration of 

 experiment. 



First day. 



Total. 



Per 



kilo- 

 gram 



of 

 body- 



wt. 



Second day. 



Total. 



Per 



kilo- 

 gram 



of 

 body- 

 weight. 



Third day. 



Total. 



Per 



kilo- 

 gram 



of 



body- 



wt. 



Fourth day. 



Total. 



Per 



kilo- 

 gram 



of 

 body- 



wt. 



59.. 

 68.. 

 69.. 

 71.. 

 73.. 

 75.. 

 77.. 

 79.. 

 80.. 

 81.. 

 82.. 

 83.. 

 85.. 

 89.. 



B. F. D., Dec. 18-20, 1903. . . 

 A. L. L., Apr. 27-28, 1904. . . 

 A. L . L. , Dec. 16-19, 1904 . . . 



S.A.B., Jan. 7-10, 1905 



S. A. B., Jan. 28-Feb. 1, 1905 

 S. A. B., Mar. 4-10, 1905.... 

 S.A.B., Apr. 8-11,1905.... 

 H.E.S.,Oct. 13-14, 1905... 

 C.R.Y., Oct. 27-28, 1905... 

 A. H. M., Nov. 21-22, 1905. . 

 H. C. K., Nov. 24-25, 1905. . 

 H. R.D., Dec. 5-6, 1905. ... 

 N.M.P., Dec. 9-10, 1905.... 

 D.W., Jan. 10-11,1906 



Gms. 



89.2 

 112.5 

 103.8 

 181.6 

 135.3 



64.9 



92.7 

 117.6 

 103.6 



28.7 

 165.6 



32.8 

 146.0 

 165.6 



Average 110 . 



Gms. 



33 



56 

 41 

 15 

 31 

 09 



1.51 

 2.08 

 1.51 



.47 

 2.33 



.59 

 2.18 

 2.12 



Gms. 

 59.4 

 72.6 

 31.5 

 29.7 

 18.1 

 23.1 

 14.9 

 40.0 

 17.1 

 '25.7 

 44.7 

 41.6 

 91.6 

 39.6 



1.69 2 40. 3 



Gm s. 



0.90 



1.03 

 .43 

 .52 

 .31 

 .39 

 .25 

 .72 

 .26 

 1 .43 

 .64 

 .76 



1.40 

 .51 



Gms 

 4.2 



2 0.62 



32.7 



22.0 



7.4 



5.4 



58.9 



21.8 



Gms 

 0.06 



Gms. 



Gms. 



.46 

 .39 

 .13 

 .09 



1.00 



15.30.21 

 25.3 .46 

 21.6 .39 



25.2 

 29.2 



.44 

 .51 



0.36 



23.30.40 



Ex- 

 peri- 

 ment 

 num- 

 ber. 



Subject and duration of 

 experiment. 



Fifth day. 



Total. 



Per 



kilo- 

 gram 



of 

 body- 

 weight. 



Sixth day. 



Total. 



Per 



kilo- 

 gram 



of 

 body- 

 weight. 



Seventh day. 



Total. 



Per 



kilo- 

 gram 



of 

 body- 

 weight. 



73... 



75... 



S. A. B., Jan. 28-Feb. 1, 1905 

 S.A.B., Mar. 4-10, 1905.... 



Average 



Gms. 



40.8 



8.2 



8.2 



Gms. 



H).20 



.14 



2 0.14 



Gms. 

 21.' 7 



21.7 



Gms. 

 6.38 



Gms. 

 18. '7 



0.38 



18.7 



Gms. 

 0^33 



0.33 



1 Glycogen gained. 



2 Omitting glycogen gained. 



The figures above show in a striking manner the great possibilities of error 

 involved in the assumption made in all earlier fasting experiments with men, 

 that the store of glycogen in the body is not materially drawn upon during the 

 earlier days of fasting. On the first day of fast the amounts katabolized 

 varied in these 14 experiments from 28.7 grams to 181.6 grams, and on the 



