;,ls Influence of Inanition on Metabolism. 



These data seemed to indicate that in general the fasting katabolism is 

 reached after 24 hours of inanition. The results of the experiments on food 

 ingestion after short fasts will he published in a subsequent report. Since 

 these embody a type of experiment somewhat different from the food experi- 

 ments here reported, it seems best to include with the fasting experiments 

 the data obtained from the food experiments immediately following them. 



The results obtained have much general interest other than that regarding 

 the matter of digestibility or the effect on general metabolism, and although 

 the special discussion of the effect of the ingestion of food on metabolism will 

 be taken up in a subsequent publication certain features are here discussed. 

 Furthermore, in the discussion of the fasting experiments the data for the sub- 

 sequent days with food have frequently been inserted in the derived tables for 

 the purpose of comparison. Thus, some discussion of the effect of ingestion of 

 food has already been given. It is the purpose of this discussion to outline 

 some of the more important points to be emphasized in connection with the 

 data for food experiments Nos. 70, 72, 74, and 76. 



Aside from the data obtained from the experiments with food inside the 

 respiration chamber, the data for the food, feces, and urine were obtained for 

 periods of considerable length following food experiment No. 76 and fasting 

 experiment No. 77, and many interesting data on the third point, i. e., recoup- 

 ment after fasting, were secured. 



In these experiments the total income of food and the outgo in urine and 

 feces were determined. Since the primary object was to study the intake and 

 output of nitrogen, they have been designated Nitrogen Metabolism Experi- 

 ments, Nos. 1 and 2. 



The results of these experiments on the long-continued ingestion of food 

 are here presented and discussed. The detailed statistical data have been given 

 on pages 274 to 299. 



Pbecautions in Feeding. 

 It is commonly considered among professional fasters and others whose 

 experience with fasting subjects has been extended, that especial caution should 

 be exercised in administering food after a fast. The ingestion of a large 

 amount of solid food into the stomach after a long period of rest, causes serious 

 disturbance. Hence, in the experiments reported herewith, special care was 

 taken to avoid any complications which might result from over-feeding. In 

 general, the subjects were given small amounts of milk (less than half a glass) 

 from time to time, and no solid food was administered until several hours after 

 the fast ended. The previous experience of the subject S. A. B. had convinced 

 him that his i'nsts were best broken by taking orange juice. Hence, his diet for 

 the first day contained only orange juice and small quantities of milk. In 

 subsequent experiments,, the orange juice was supplemented by a small amount 



